Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Nov;15(11):1309-13.
doi: 10.1016/j.sleep.2014.06.013. Epub 2014 Aug 1.

Adaptive servo-ventilation as treatment of persistent central sleep apnea in post-acute ischemic stroke patients

Anne-Kathrin Brill  1 , Regula Rösti  2 , Jacqueline Pichler Hefti  2 , Claudio Bassetti  3 , Matthias Gugger  2 , Sebastian R Ott  2
Affiliations

Adaptive servo-ventilation as treatment of persistent central sleep apnea in post-acute ischemic stroke patients

Anne-Kathrin Brill et al. Sleep Med. 2014 Nov.

Abstract

Background: Adaptive servo-ventilation (ASV) is a well-established treatment of central sleep apnea (CSA) related to congestive heart failure (CHF). Few studies have evaluated the effectiveness and adherence in patients with CSA of other etiologies, and even less is known about treatment of CSA in patients of post ischemic stroke.

Methods: A single-centre retrospective analysis of ASV treatment for CSA in post-acute ischemic stroke patients without concomitant CHF was performed. Demographics, clinical data, sleep studies, ventilator settings, and adherence data were evaluated.

Results: Out of 154 patients on ASV, 15 patients had CSA related to ischemic stroke and were started on ASV a median of 11 months after the acute cerebrovascular event. Thirteen out of the 15 patients were initially treated with continuous positive airway pressure (11/15) and bilevel positive airway pressure (2/15) therapy with unsatisfactory control of CSA. ASV significantly improved AHI (46.7 ± 24.3 vs 8.5 ± 12/h, P = 0.001) and reduced ESS (8.7 ± 5.7 vs 5.6 ± 2.5, P = 0.08) with a mean nightly use of ASV of 5.4 ± 2.4 h at 3 months after the initiation of treatment. Results were maintained at 6 months.

Conclusion: ASV was well tolerated and clinically effective in this group of patients with persistent CSA after ischemic stroke.

Keywords: Cerebrovascular insult; Continuous positive airway pressure; Epworth Sleepiness Scale; Neurologic disorders; Sleep disordered breathing; Stroke distribution.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

LinkOut - more resources

-