The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies

doi:10.3390/foods7040058

Review

. 2018 Apr 11;7(4):58.

doi: 10.3390/foods7040058.

The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies

Brett J West¹, Shixin Deng², Fumiyuki Isami³, Akemi Uwaya⁴, Claude Jarakae Jensen⁵

Affiliations

¹ Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. brett_west@morinda.com.
² Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. shixin_deng@morinda.com.
³ Research and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. fumiyuki_isami@jp.morinda.com.
⁴ Research and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. akemi_uwaya@jp.morinda.com.
⁵ Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. jarakae_jensen@morinda.com.

PMID: 29641454
PMCID: PMC5920423
DOI: 10.3390/foods7040058

Review

The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies

Brett J West et al. Foods. 2018.

. 2018 Apr 11;7(4):58.

doi: 10.3390/foods7040058.

Authors

Brett J West¹, Shixin Deng², Fumiyuki Isami³, Akemi Uwaya⁴, Claude Jarakae Jensen⁵

Affiliations

¹ Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. brett_west@morinda.com.
² Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. shixin_deng@morinda.com.
³ Research and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. fumiyuki_isami@jp.morinda.com.
⁴ Research and Development, Morinda, Inc., 3-2-2 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. akemi_uwaya@jp.morinda.com.
⁵ Research and Development, Morinda, Inc., 737 East 1180 South, American Fork, UT 84003, USA. jarakae_jensen@morinda.com.

PMID: 29641454
PMCID: PMC5920423
DOI: 10.3390/foods7040058

Abstract

Noni juice is a globally popular health beverage originating in the tropics. Traditional Tahitian healers believe the noni plant to be useful for a wide range of maladies, and noni juice consumers throughout the world have similar perceptions. Nevertheless, human clinical trials are necessary for a precise understanding of what the health benefits of noni juice are. A review of published human intervention studies suggests that noni juice may provide protection against tobacco smoke-induced DNA damage, blood lipid and homocysteine elevation as well as systemic inflammation. Human intervention studies also indicate that noni juice may improve joint health, increase physical endurance, increase immune activity, inhibit glycation of proteins, aid weight management, help maintain bone health in women, help maintain normal blood pressure, and improve gum health. Further, these studies point to notable antioxidant activity in noni juice, more so than other fruit juices which served as trial placebos. It is this antioxidant effect and its interaction with the immune system and inflammation pathways that may account for many of the observed health benefits of noni juice. However, the existing evidence does have some limitations as far as its general application to noni juice products; all the peer-reviewed human interventions studies to date have involved only one source of French Polynesian noni juice. Geographical factors and variations in processing methods are known to produce commercial noni juice products with divergent phytochemical and nutrient compositions. Therefore, other sources of noni products may have different toxicological and pharmacological profiles.

Keywords: Morinda citrifolia; antioxidant; clinical trial; immune system; inflammation; noni juice.

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Conflict of interest statement

The authors declare no conflict of interest. The authors are employed in the research and development department of Morinda, Inc., a manufacturer of noni juice.

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References

1. European Food Safety Authority Scientific Opinion of the Panel on Dietetic Products Nutrition and Allergies on a request from the European Commission on the safety of Tahitian Noni® ‘Morinda citrifolia (Noni) fruit puree and concentrate’ as a novel food ingredient. EFSA J. 2009;998:1–16. doi: 10.2903/j.efsa.2009.998. - DOI
1. European Commission Commission decision of 5 June 2003 authorising the placing on the market of “noni juice “(juice of the fruit of Morinda citrifolia L.) as a novel food ingredient under regulation (EC) No 258/97 of the European parliament and of the council. [(accessed on 11 December 2017)];Off. J. Eur. Union L 144. 2003 46:12. Available online: http://data.europa.eu/eli/dec/2003/426/oj.
1. China Food and Drug Administration June 27, 2011 Health Food Record Information Release. [(accessed on 11 December 2017)]; Available online: http://www.sda.gov.cn/WS01/CL0613/63379.html.
1. Morton J. The ocean-going Noni, or Indian Mulberry (Morinda citrifolia, Rubiaceae) and some of its “colorful“ relatives. Econ. Bot. 1992;46:241–256. doi: 10.1007/BF02866623. - DOI
1. Stone B.C. Morinda Linnaeus. Micronesica. 1970;6:1–659.

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[1] European Food Safety Authority Scientific Opinion of the Panel on Dietetic Products Nutrition and Allergies on a request from the European Commission on the safety of Tahitian Noni® ‘Morinda citrifolia (Noni) fruit puree and concentrate’ as a novel food ingredient. EFSA J. 2009;998:1–16. doi: 10.2903/j.efsa.2009.998. - DOI

[2] European Food Safety Authority Scientific Opinion of the Panel on Dietetic Products Nutrition and Allergies on a request from the European Commission on the safety of Tahitian Noni® ‘Morinda citrifolia (Noni) fruit puree and concentrate’ as a novel food ingredient. EFSA J. 2009;998:1–16. doi: 10.2903/j.efsa.2009.998. - DOI

[3] European Commission Commission decision of 5 June 2003 authorising the placing on the market of “noni juice “(juice of the fruit of Morinda citrifolia L.) as a novel food ingredient under regulation (EC) No 258/97 of the European parliament and of the council. [(accessed on 11 December 2017)];Off. J. Eur. Union L 144. 2003 46:12. Available online: http://data.europa.eu/eli/dec/2003/426/oj.

[4] European Commission Commission decision of 5 June 2003 authorising the placing on the market of “noni juice “(juice of the fruit of Morinda citrifolia L.) as a novel food ingredient under regulation (EC) No 258/97 of the European parliament and of the council. [(accessed on 11 December 2017)];Off. J. Eur. Union L 144. 2003 46:12. Available online: http://data.europa.eu/eli/dec/2003/426/oj.

[5] China Food and Drug Administration June 27, 2011 Health Food Record Information Release. [(accessed on 11 December 2017)]; Available online: http://www.sda.gov.cn/WS01/CL0613/63379.html.

[6] China Food and Drug Administration June 27, 2011 Health Food Record Information Release. [(accessed on 11 December 2017)]; Available online: http://www.sda.gov.cn/WS01/CL0613/63379.html.

[7] Morton J. The ocean-going Noni, or Indian Mulberry (Morinda citrifolia, Rubiaceae) and some of its “colorful“ relatives. Econ. Bot. 1992;46:241–256. doi: 10.1007/BF02866623. - DOI

[8] Morton J. The ocean-going Noni, or Indian Mulberry (Morinda citrifolia, Rubiaceae) and some of its “colorful“ relatives. Econ. Bot. 1992;46:241–256. doi: 10.1007/BF02866623. - DOI

[9] Stone B.C. Morinda Linnaeus. Micronesica. 1970;6:1–659.

[10] Stone B.C. Morinda Linnaeus. Micronesica. 1970;6:1–659.

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The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies

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The Potential Health Benefits of Noni Juice: A Review of Human Intervention Studies

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