Inflammation, infection and atherosclerosis
- PMID: 30733074
- DOI: 10.1016/j.tcm.2019.01.004
Inflammation, infection and atherosclerosis
Abstract
Atherosclerotic cardiovascular disease is a leading cause of death in much of the world. Adoption of a healthy lifestyle and cholesterol lowering are the key measures used to prevent major complications of atherosclerosis. Recent data have identified a critical role for inflammation mediated through activation of both innate and adaptive immune pathways in the pathophysiology of atherosclerosis opening up opportunities for development of anti-inflammatory interventions that could supplement risk factor modification and lipid lowering as an approach to further reducing the burden of atherosclerotic cardiovascular disease.
Keywords: Atherosclerosis; Vascular inflammation.
Copyright © 2019. Published by Elsevier Inc.
Comment in
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Editorial commentary: Arson in the artery: Who set the atheroma aflame?Trends Cardiovasc Med. 2019 Nov;29(8):473-475. doi: 10.1016/j.tcm.2019.03.006. Epub 2019 Mar 28. Trends Cardiovasc Med. 2019. PMID: 30956033
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