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. 1993 Aug 21;163(4):439-48.
doi: 10.1006/jtbi.1993.1129.

Effects of high frequency stimulation on cardiac tissue with an inexcitable obstacle

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Effects of high frequency stimulation on cardiac tissue with an inexcitable obstacle

A V Panfilov et al. J Theor Biol. .

Abstract

We study numerically the effects of high-frequency stimulation in excitable cardiac tissue with an inexcitable obstacle using a Fitz-Hugh Nagumo type model. We show that if the frequency of stimulation is sufficiently high and the size of the inexcitable obstacle is sufficiently large, then a re-entrant pattern can be initiated. We also show that with overdrive stimulation a re-entrant pattern can be removed provided there are no obstacles at which new re-entrant patterns are created.

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