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. 2014 Mar;30(1):39-44.
doi: 10.5487/TR.2014.30.1.039.

Association between Urinary Bisphenol A and Waist Circumference in Korean Adults

Ahra Ko  1 , Myung-Sil Hwang  1 , Jae-Hong Park  1 , Hui-Seung Kang  1 , Hee-Seok Lee  1 , Jin-Hwan Hong  1
Affiliations

Association between Urinary Bisphenol A and Waist Circumference in Korean Adults

Ahra Ko et al. Toxicol Res. 2014 Mar.

Abstract

Bisphenol A (BPA) is widely used in the production of polycarbonate plastics, epoxy resins, and food and beverage containers. In the present study, we aimed to investigate the relationship between urinary concentrations of BPA and waist circumference in Korean adults. A total of 1,030 Korean adults (mean age, 44.3 ± 14.6 years) were enrolled in the study on the integrated exposure to hazardous materials for safety control, conducted by the Ministry of Food and Drug Safety from 2010 to 2012. Abdominal obesity was defined as having a waist circumference of at least 90 cm and 85 cm for men and women, respectively. The participants were divided into 4 groups according to the urinary BPA concentration quartile. Waist circumference was significantly higher among subjects with a urinary BPA concentration in the highest quartile relative to those in the lowest quartile (p = 0.0071). Linear regression analysis revealed a significant positive association between urinary BPA concentrations and body mass index, body fat, after adjusting for potential confounders. Moreover, subjects with urinary BPA concentrations in the fourth quartile were more likely to be obese compared to those with urinary BPA concentrations in the first quartile (odds ratio, 1.938; 95% CI: 1.314~2.857; p for trend = 0.0106). These findings provide evidence for a positive association between urinary BPA concentration and waist circumference in Korean adults.

Keywords: Bisphenol A; Korean adults; Waist circumference.

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References

    1. Vandenberg L.N., Hauser R., Marcus M., Olea N., Welshons W.V. Human exposure to bisphenol A (BPA). Reprod. Toxicol. (2007);24:139–177. doi: 10.1016/j.reprotox.2007.07.010. - DOI - PubMed
    1. Vandenberg L.N., Chahoud I., Heindel J.J., Padmanabhan V., Paumgartten F.J., Schoenfelder G. Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A. Environ. Health Perspect. (2010);118:1055–1070. doi: 10.1289/ehp.0901716. - DOI - PMC - PubMed
    1. Braun J.M., Kalkbrenner A.E., Calafat A.M., Yolton K., Ye X., Dietrich K.N., Lanphear B.P. Impact of earlylife bisphenol A exposure on behavior and executive function in children. Pediatrics. (2011);128:873–882. doi: 10.1542/peds.2011-1335. - DOI - PMC - PubMed
    1. Li D., Zhou Z., Qing D., He Y., Wu T., Miao M., Wang J., Weng X., Ferber J.R., Herrinton L.J., Zhu Q., Gao E., Checkoway H., Yuan W. Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction. Hum. Reprod. (2010);25:519–527. doi: 10.1093/humrep/dep381. - DOI - PubMed
    1. Li D.K., Zhou Z., Miao M., He Y., Qing D., Wu T., Wang J., Weng X., Ferber J., Herrinton L.J., Zhu Q., Gao E., Yuan W. Relationship between urine bisphenol-A level and declining male sexual function. J. Androl. (2010);31:500–506. doi: 10.2164/jandrol.110.010413. - DOI - PubMed

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