The Transmembrane Domain of CEACAM1-4S Is a Determinant of Anchorage Independent Growth and Tumorigenicity
Figure 5
Anchorage Independent Growth in Soft Agar.
(A–I) show the appearance of colonies formed by the various CEACAM1-4S sublines after 3 weeks in soft agar: (A) G424L; (B) G432L; (C) G424L and G432L; (D) Y445V; (E) Y448V; (F) Y445V and Y448V; (G) G424L, G432L and Y445V; (H) G424L, G432L and Y448V; (I) G424L, G432L, Y445V and Y448V.