Fgf21 Impairs Adipocyte Insulin Sensitivity in Mice Fed a Low-Carbohydrate, High-Fat Ketogenic Diet
Figure 1
Body weights and blood parameters in mice fed KD.
(A) Blood β-hydroxybutyrate levels in 3-month-old mice fed KD for 6 days or 14 days, or NC (n = 3–8 per group; **, P<0.01 vs. day 0). (B) Body weights in 3-month-old mice fed KD for 6 days or 14 days, or NC (n = 5–28per group; *, P<0.05; **, P<0.01 vs. day 0). (C–F) Blood NEFA, triglyceride, glucose, and insulin levels in 3-month-old mice fed KD for 6 days or 14 days, or NC (n = 4–12 per group; **, P<0.01 vs. day 0).