Explore the latest in bleeding and transfusion, including trauma and resuscitation, transfusion thresholds and complications, and more.
This post hoc analysis of a randomized clinical trial investigates if patients 80 years and older with atrial fibrillation benefit from lower-dose anticoagulants even in the absence of prespecified dose-reduction criteria.
This secondary analysis of the ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) randomized clinical trial investigates if there are sex-specific differences in the safety and effectiveness of 2 aspirin doses for the secondary prevention of atherosclerotic cardiovascular disease (CVD).
This secondary analysis of a randomized clinical trial compares neurodevelopmental outcomes after the use of umbilical cord milking or early cord clamping in near-term or term nonvigorous infants at age 2 years.
This observational study assesses incidence of wound hematoma diagnoses up to 6 weeks post partum among obstetric patients who received thromboprophylaxis according to less selective vs more selective hospital chemoprophylaxis protocols.
This consensus statement describes the guideline development process for recommending a transfusion strategy in newborns with less than 30 weeks’ gestational age.
In this narrative medicine essay, when a physician’s mother begins experiencing postmenopausal bleeding, the author wonders what it would be like to hear someone’s signs and symptoms and not automatically begin to build a differential.
A 28-year-old man presented with decreased visual acuity in his right eye for the past 2 weeks. Examination revealed dilated and tortuous veins, Roth spots, and white intraretinal agglomerates. What would you do next?
This post hoc analysis of the ELAN randomized clinical trial investigates whether infarct size modifies the safety and efficacy of early vs late direct oral anticoagulation initiation after ischemic stroke in individuals with atrial fibrillation.
This systematic review and meta-analysis examines the frequency of presenting red flag signs and symptoms among individuals with early-onset colorectal (EOCRC), the associations of these signs and symptoms with risk of EOCRC, and variations in time from sign or symptom presentation to diagnosis.
This cohort study analyzes data for patients who underwent pancreaticoduodenectomy to determine the frequency of gastroduodenal artery bleeding compared with other sites and the results of mitigation strategies.
This cohort study investigates if there is an increased risk of symptomatic intracerebral hemorrhage associated with prestroke antiplatelet therapy after treatment in intravenous alteplase.
This network meta-analysis evaluates different dual antiplatelet therapy treatment regimens for patients with minor, nondisabling, acute ischemic stroke.
This randomized clinical trial investigates if patients with high bleeding risk and a history of myocardial infarction (MI) would benefit from complete vs culprit-only revascularization.
This secondary analysis of a randomized clinical trial evaluates the temporal association between 72-hour hazard periods of exposure to red blood cell (RBC) transfusions and necrotizing enterocolitis among extremely low-birthweight infants randomized to higher or lower hemoglobin transfusion thresholds.
This JAMA Clinical Guidelines Synopsis summarizes the 2023 American College of Gastroenterology guidelines on management of patients with acute lower gastrointestinal bleeding.
This randomized clinical trial analyzes data for patients with acute noncardioembolic stroke who were given intravenous tirofiban within 24 hours of stroke onset to gauge its effect on early neurological deterioration compared with oral aspirin.
This randomized clinical trial evaluates clopidogrel monotherapy vs dual antiplatelet therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventions who are at high bleeding and ischemic risk.
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