September 1, 2020, Vol 324, No. 9, Pages 823-908

In This Issue of JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2020;324(9):e200035. doi:10.1001/jama.2020.0035

Audio Editors' Summary: Surgical Tidal Volumes and Postop Complications, New-Onset Postop Afib and Stroke, Review of Bariatric Surgery, and more

Original Investigation

Effect of Intraoperative Low Tidal Volume vs Conventional Tidal Volume on Postoperative Pulmonary Complications in Patients Undergoing Major Surgery: A Randomized Clinical Trial

Dharshi Karalapillai, MD; Laurence Weinberg, MD; Philip Peyton, MD; et al.

Abstract Full Text

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JAMA. 2020;324(9):848-858. doi:10.1001/jama.2020.12866

This randomized clinical trial compares the effect of intraoperative ventilation with low vs conventional tidal volume (6 vs 10 mL/kg predicted body weight) on pulmonary complications in the first 7 postoperative days among patients undergoing major surgery lasting longer than 2 hours.

Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US

Katherine A. Auger, MD, MSc; Samir S. Shah, MD, MSCE; Troy Richardson, PhD; et al.

Abstract Full Text

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JAMA. 2020;324(9):859-870. doi:10.1001/jama.2020.14348

This population epidemiology study estimates associations of school closures in the US and the timing of those closures in March 2020 with change in daily coronavirus disease 2019 (COVID-19) incidence and mortality through the first week of May, accounting for other contemporaneous public health interventions.

Video: COVID-19 and School Reopenings

Conversations with Dr Bauchner: COVID-19 and School Reopenings
Audio Clinical Review: How to Reopen Schools in the COVID-19 Era
Audio Clinical Review: Gyms, Restaurants, Mass Transit, and Community COVID-19 Exposures

Editorial
COVID-19 and School Closures
Julie M. Donohue, PhD; Elizabeth Miller, MD, PhD

JAMA
- Video: COVID-19 and School Reopenings
- Conversations with Dr Bauchner: COVID-19 and School Reopenings

Association of New-Onset Atrial Fibrillation After Noncardiac Surgery With Subsequent Stroke and Transient Ischemic Attack

Konstantinos C. Siontis, MD; Bernard J. Gersh, MB, ChB, DPhil; Susan A. Weston, MS; et al.

Abstract Full Text

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JAMA. 2020;324(9):871-878. doi:10.1001/jama.2020.12518

This retrospective study compared the rate of ischemic stroke or transient ischemic attack among Olmstead County, Minnesota, residents with vs without new-onset postoperative atrial fibrillation after undergoing noncardiac surgery.

Research Letter

Prevalence of SARS-CoV-2 Antibodies in Health Care Personnel in the New York City Area

Joseph Moscola, PA, MBA; Grace Sembajwe, DSc, MSc, CIH; Mark Jarrett, MD, MBA, MS; et al.

Abstract Full Text

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JAMA. 2020;324(9):893-895. doi:10.1001/jama.2020.14765

This seroprevalence survey study describes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity among health care workers at a New York City–based health system by age, sex, race, county of residence, and prior PCR-confirmed viral exposure.

Incidence of Malformations After Early Pregnancy Exposure to Modafinil in Sweden and Norway

Carolyn E. Cesta, PhD; Anders Engeland, PhD; Pär Karlsson, MSc; et al.

Abstract Full Text

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JAMA. 2020;324(9):895-897. doi:10.1001/jama.2020.9840

This pharmacoepidemiology study uses Scandinavian birth registry data to estimate the association between modafinil use during early pregnancy and major congenital malformations among infants born in Norway and Sweden between 2005-2006 and 2016-2017.

Viewpoint

Reopening K-12 Schools During the COVID-19 Pandemic: A Report From the National Academies of Sciences, Engineering, and Medicine

Kenne A. Dibner, PhD; Heidi A. Schweingruber, PhD; Dimitri A. Christakis, MD, MPH

Abstract Full Text

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JAMA. 2020;324(9):833-834. doi:10.1001/jama.2020.14745

This Viewpoint summarizes recommendations made in a National Academies of Sciences, Engineering, and Medicine report about how to safely reopen and operate elementary and secondary schools for the 2020-2021 school year, which emphasizes the need for partnerships with public health officials and community leaders, and for transparent communication of risks and rewards that will result from every policy decision.

Editorial
COVID-19 and School Closures
Julie M. Donohue, PhD; Elizabeth Miller, MD, PhD

JAMA
- Video: COVID-19 and School Reopenings
- Conversations with Dr Bauchner: COVID-19 and School Reopenings

Women Physicians and the COVID-19 Pandemic

Linda Brubaker, MD

Abstract Full Text

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JAMA. 2020;324(9):835-836. doi:10.1001/jama.2020.14797

This Viewpoint describes how the COVID-19 pandemic has made more obvious the work-life imbalance inherent in the practice of medicine and how the moment offers the profession the chance to recalibrate gender role stereotypes that have traditionally disadvantaged the careers of women physicians and researchers.

Editorial
Consequences of the COVID-19 Pandemic on Manuscript Submissions by Women
Melina R. Kibbe, MD

JAMA Surg

Universal Masking in the United States: The Role of Mandates, Health Education, and the CDC

Lawrence O. Gostin, JD; I. Glenn Cohen, JD; Jeffrey P. Koplan, MD, MPH

Abstract Full Text

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JAMA. 2020;324(9):837-838. doi:10.1001/jama.2020.15271

This Viewpoint proposes legal and policy options for promoting universal face mask wearing in the US and, recognizing the limits of state-by-state implementation, proposes strengthening the authority, independence, and funding of the CDC to enact responses to this and future comparable public health emergencies.

Conversations with Dr Bauchner: Coronavirus and US State Departments of Health

Editorial
Universal Masking to Prevent SARS-CoV-2 Transmission—The Time Is Now
John T. Brooks, MD; Jay C. Butler, MD; Robert R. Redfield, MD

JAMA
- Video: Coronavirus Update With Eric Topol, MD
- Video: Coronavirus Update With CDC Director Robert R. Redfield, MD
- Conversations with Dr Bauchner: Coronavirus Update With CDC Director Robert R. Redfield, MD
- Conversations with Dr Bauchner: Coronavirus Update With Eric Topol, MD

National Hospital Quality Rankings: Improving the Value of Information in Hospital Rating Systems

Jonathan A. Bae, MD; Lesley H. Curtis, PhD; Adrian F. Hernandez, MD, MHS

Abstract Full Text

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JAMA. 2020;324(9):839-840. doi:10.1001/jama.2020.11165

This Viewpoint uses US News & World Report’s annual hospital rankings to discuss how such efforts typically disadvantage hospitals caring for patients of lower socioeconomic status (SES) in regions with poorer population health, and argues for transparent and accurate ratings methods that use patient-centric quality measures and account for population SES.

Conversations with Dr Bauchner: Improving the Value of Information in Hospital Rating Systems

Scientific Discovery and the Future of Medicine

Progress in Multiple Sclerosis Research: An Example of Bedside to Bench

Stephen L. Hauser, MD

Abstract Full Text

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JAMA. 2020;324(9):841-842. doi:10.1001/jama.2020.1522

This Viewpoint attributes improved understanding of the role of autoantibodies and B-cell activity in MS pathogenesis and the development of effective therapies to the ability of physician-scientists to bring clinical insights to laboratory research and it emphasizes the importance of supporting and encouraging these investigators to reinvigorate science at the bedside.

Audio Clinical Review: Diagnosis and Treatment of Multiple Sclerosis—A Review

A Piece of My Mind

Non Sei Solo

Mark C. Henderson, MD

Abstract Full Text

JAMA. 2020;324(9):843-844. doi:10.1001/jama.2020.14420

In this narrative medicine essay a father recalls the traumatic death of his healthy young son and the steps he and his family took to overcome their guilt, repair their relationships, and honor the boy’s life.

Editorial

COVID-19 and School Closures

Julie M. Donohue, PhD; Elizabeth Miller, MD, PhD

Abstract Full Text

free access has multimedia has audio

JAMA. 2020;324(9):845-847. doi:10.1001/jama.2020.13092

Video: COVID-19 and School Reopenings

Conversations with Dr Bauchner: COVID-19 and School Reopenings

Review

Benefits and Risks of Bariatric Surgery in Adults: A Review

David E. Arterburn, MD, MPH; Dana A. Telem, MD, MPH; Robert F. Kushner, MD; et al.

Abstract Full Text

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JAMA. 2020;324(9):879-887. doi:10.1001/jama.2020.12567

Precis This narrative review summarizes the efficacy and safety of bariatric surgery, mainly sleeve gastrectomy and the Roux-en-Y procedure, in assisting weight loss and in patients with type 2 diabetes and other obesity-related comorbidities.

Audio Clinical Review: Update on Bariatric Surgery—2020

JAMA Insights

Clinical Update

Primary Care Treatment of Patients Following Bariatric Surgery in 2020

Yijun Chen, MD; Zhaoping Li, MD; Erik Dutson, MD

Abstract Full Text

JAMA. 2020;324(9):888-889. doi:10.1001/jama.2020.14061

This JAMA Insights Clinical Update reviews long-term complications of bariatric surgery, including GERD, gallstones, hypoglycemia, substance use disorder, and vitamin and other nutritional deficiencies, and proposes a schedule of testing and management strategies for each.

From The Medical Letter on Drugs and Therapeutics

Rimegepant (Nurtec ODT) for Acute Treatment of Migraine

Abstract Full Text

JAMA. 2020;324(9):890-891. doi:10.1001/jama.2020.8493

This Medical Letter review summarizes evidence supporting the use of rimegepant (Nurtec), a small-molecule calcitonin gene-related peptide receptor antagonist, for acute treatment of migraine with or without aura in adults.

Medical News & Perspectives

Researchers Strive to Recruit Hard-Hit Minorities Into COVID-19 Vaccine Trials

Mary Chris Jaklevic, MSJ

Abstract Full Text

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JAMA. 2020;324(9):826-828. doi:10.1001/jama.2020.11244

This Medical News article discusses efforts to ensure participation of racial and ethnic minorities in clinical trials of COVID-19 vaccines.

Video: Coronavirus Vaccine FDA Update

JAMA Medical News Audio: August 2020 Medical News Summary
Conversations with Dr Bauchner: Coronavirus Vaccine FDA Update

Editorial
Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine
Howard Bauchner, MD; Preeti N. Malani, MD, MSJ; Joshua Sharfstein, MD

JAMA
- Video: Coronavirus Vaccine Update With Anthony Fauci
- Video: Coronavirus Update With Anthony Fauci - October 28, 2020
- Video: Coronavirus Q&A With Anthony Fauci, MD – September 25, 2020
- Video: Coronavirus Update With Michael T. Osterholm, PhD, MPH
- Video: COVID-19 Vaccine Approval and the FDA
- Conversations with Dr Bauchner: COVID-19 Vaccine Approval and the FDA
- Conversations with Dr Bauchner: Coronavirus Update With Michael T. Osterholm, PhD, MPH
- Conversations with Dr Bauchner: Coronavirus Q&A With Anthony Fauci, MD – September 25, 2020
- Conversations with Dr Bauchner: Coronavirus Update With Anthony Fauci - October 28, 2020
- Conversations with Dr Bauchner: Coronavirus Vaccine Update With Anthony Fauci

News From the Food and Drug Administration

New FDA-EPA Protocol Covers Agricultural Water Safety

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2020;324(9):832. doi:10.1001/jama.2020.15848

CAR-T Therapy Is Approved for Mantle Cell Lymphoma

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2020;324(9):832. doi:10.1001/jama.2020.15456

FDA Targets Illegal Hangover Relief

Rebecca Voelker, MSJ

Abstract Full Text

JAMA. 2020;324(9):832. doi:10.1001/jama.2020.15849

The JAMA Forum

The Importance of Reestablishing a Pandemic Preparedness Office at the White House

Gail Wilensky, PhD

Abstract Full Text

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JAMA. 2020;324(9):830-831. doi:10.1001/jama.2020.15525

Bench to Bedside

RNA Aptamers Deliver Chemotherapy Directly to Tumors

Tracy Hampton, PhD

Abstract Full Text

JAMA. 2020;324(9):829. doi:10.1001/jama.2020.14464

Poetry and Medicine

The Nerve

Mary Meriam, MFA

Abstract Full Text

JAMA. 2020;324(9):902. doi:10.1001/jama.2020.7276

JAMA Revisited

Rambling Notes of a Roving Doctor

Abstract Full Text

JAMA. 2020;324(9):903. doi:10.1001/jama.2019.13598

JAMA Patient Page

Sleeve Gastrectomy

Brian C. Brajcich, MD, MS; Eric S. Hungness, MD

Abstract Full Text

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JAMA. 2020;324(9):908. doi:10.1001/jama.2020.14775

This JAMA Patient Page explains who should undergo gastric sleeve procedure, a type of obesity surgery; how to prepare for it; and what to expect afterward.

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