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Molecular interactions of (−)-CG binding to mutant L858R EGFR. All the interacting residues are listed with the number of hydrogen bonds and non-bonded contacts.
| Interacting residue | Hydrogen bonds | Non-bonded contacts |
|---|---|---|
| Leu-718 | 1 | |
| Phe-723 | 4 | |
| Val-726 | 3 | |
| Ala-743 | 1 | |
| Lys-745 | 10 | |
| Glu-762 | 1 | |
| Met-766 | 4 | |
| Thr-790 | 2 | |
| Leu-792 | 1 | |
| Met-793 | 1 | 3 |
| Gly-796 | 1 | |
| Leu-844 | 5 | |
| Asp-855 | 6 |
