Skip to main content

This is a preview of improvements coming to the PMC website in October 2024. Learn more

Return to current site
. 2010 Oct 28;6(10):e1001179. doi: 10.1371/journal.pgen.1001179

Figure 6. A central role for NHK-1 kinase in meiotic progression.

Figure 6

NHK-1 promotes nuclear reorganisation from a recombination phase to a post-recombination phase, including karyosome formation, synaptonemal complex disassembly and condensin loading. NHK-1 directly phosphorylates BAF that anchors meiotic chromosomes to the nuclear envelope. DSBs activate the meiotic recombination checkpoint that suppresses NHK-1 kinase to prevent nuclear reorganisation.

-