Figure 4. Intact Electron Complex Activity in Myo-PGC-1α in response to exercise.
A.) Enzymatic traces of complex activities B.) Rotenone sensitive NADH dehydrogenase activity (Complex I). C.) Succinate-cytochrome creductase activity (Complex II+III). D.) Glycerol-3-phosphate dehydrogenase + Complex III, rate dependent on glycerol-3-phosphate dehydrogenase (Complex III). E.) Cytochrome oxidase activity (Complex IV).F.) ATPase activity (Complex V). Myo-PGC-1αKO (red bar) and littermate controls (white bar). Error bars indicate s.e.m.; n >3 per group in all panels. * - P<0.05 compared to control; # - P<0.05 compared to sedentary.