The core meiotic transcriptome in budding yeasts
- PMID: 11101837
- DOI: 10.1038/82539
The core meiotic transcriptome in budding yeasts
Abstract
We used high-density oligonucleotide microarrays to analyse the genomes and meiotic expression patterns of two yeast strains, SK1 and W303, that display distinct kinetics and efficiencies of sporulation. Hybridization of genomic DNA to arrays revealed numerous gene deletions and polymorphisms in both backgrounds. The expression analysis yielded approximately 1,600 meiotically regulated genes in each strain, with a core set of approximately 60% displaying similar patterns in both strains. Most of these (95%) are MATa/MATalpha-dependent and are not similarly expressed in near-isogenic meiosis-deficient controls. The transcript profiles correlate with the distribution of defined meiotic promoter elements and with the time of known gene function.
Similar articles
-
CLN1 and its repression by Xbp1 are important for efficient sporulation in budding yeast.Mol Cell Biol. 2000 Jan;20(2):478-87. doi: 10.1128/MCB.20.2.478-487.2000. Mol Cell Biol. 2000. PMID: 10611226 Free PMC article.
-
The transcriptional program of sporulation in budding yeast.Science. 1998 Oct 23;282(5389):699-705. doi: 10.1126/science.282.5389.699. Science. 1998. PMID: 9784122
-
Effects of age on meiosis in budding yeast.Dev Cell. 2009 Jun;16(6):844-55. doi: 10.1016/j.devcel.2009.05.013. Dev Cell. 2009. PMID: 19531355 Free PMC article.
-
Meiosis: step-by-step through sporulation.Curr Biol. 1998 Jun 18;8(13):R461-3. doi: 10.1016/s0960-9822(98)70293-3. Curr Biol. 1998. PMID: 9651674 Review.
-
The nature of meiotic chromosome dynamics and recombination in budding yeast.J Microbiol. 2019 Apr;57(4):221-231. doi: 10.1007/s12275-019-8541-9. Epub 2019 Jan 22. J Microbiol. 2019. PMID: 30671743 Review.
Cited by
-
The MAPK homolog, Smk1, promotes assembly of the glucan layer of the spore wall in S. cerevisiae.Yeast. 2024 Jul;41(7):448-457. doi: 10.1002/yea.3967. Epub 2024 Jun 14. Yeast. 2024. PMID: 38874213
-
Control of meiotic entry by dual inhibition of a key mitotic transcription factor.Elife. 2024 Feb 27;12:RP90425. doi: 10.7554/eLife.90425. Elife. 2024. PMID: 38411169 Free PMC article.
-
From beer to breadboards: yeast as a force for biological innovation.Genome Biol. 2024 Jan 4;25(1):10. doi: 10.1186/s13059-023-03156-9. Genome Biol. 2024. PMID: 38178179 Free PMC article. Review.
-
Spo13/MEIKIN ensures a Two-Division meiosis by preventing the activation of APC/CAma1 at meiosis I.EMBO J. 2023 Oct 16;42(20):e114288. doi: 10.15252/embj.2023114288. Epub 2023 Sep 20. EMBO J. 2023. PMID: 37728253 Free PMC article.
-
Meiosis in budding yeast.Genetics. 2023 Oct 4;225(2):iyad125. doi: 10.1093/genetics/iyad125. Genetics. 2023. PMID: 37616582 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases