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Review
. 2001 Feb;13(1):68-75.
doi: 10.1016/s0955-0674(00)00176-9.

Asymmetric cell division: fly neuroblast meets worm zygote

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Review

Asymmetric cell division: fly neuroblast meets worm zygote

C Q Doe et al. Curr Opin Cell Biol. 2001 Feb.

Abstract

Both Drosophila neuroblasts and Caenorhabditis elegans zygotes use a conserved protein complex to establish cell polarity and regulate spindle orientation. Mammalian epithelia also use this complex to regulate apical/basal polarity. Recent results have allowed us to compare the mechanisms regulating asymmetric cell division in Drosophila neuroblasts and the C. elegans zygote.

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