Review
doi: 10.1016/s0955-0674(00)00238-6.
Roles of lipid rafts in membrane transport
Affiliations
- PMID: 11454454
- DOI: 10.1016/s0955-0674(00)00238-6
Item in Clipboard
Review
Roles of lipid rafts in membrane transport
Curr Opin Cell Biol.
2001 Aug.
Abstract
Cholesterol-sphingolipid microdomains (lipid rafts) are part of the machinery ensuring correct intracellular trafficking of proteins and lipids. The most apparent roles of rafts are in sorting and vesicle formation, although their roles in vesicle movement and cytoskeletal connections as well as in vesicle docking and fusion are coming into focus. New evidence suggests that compositionally distinct lipid microdomains are assembled and may coexist within a given membrane. Important clues have also been uncovered about the mechanisms coupling raft-dependent signaling and endocytic uptake.
Similar articles
-
The roles of ubiquitin and lipids in protein sorting along the endocytic pathway.Cell Struct Funct. 2003 Oct;28(5):443-53. doi: 10.1247/csf.28.443. Cell Struct Funct. 2003. PMID: 14745136 Review.
-
Lipids as targeting signals: lipid rafts and intracellular trafficking.Traffic. 2004 Apr;5(4):247-54. doi: 10.1111/j.1600-0854.2004.0181.x. Traffic. 2004. PMID: 15030566 Review.
-
Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane.J Cell Sci. 2004 Dec 1;117(Pt 25):5955-64. doi: 10.1242/jcs.01596. J Cell Sci. 2004. PMID: 15564373 Review.
-
Membrane curvature sorts lipids. Stabilized lipid rafts in membrane transport.EMBO Rep. 2005 May;6(5):418-9. doi: 10.1038/sj.embor.7400410. EMBO Rep. 2005. PMID: 15864292 Free PMC article. Review.
-
Transcytotic efflux from early endosomes is dependent on cholesterol and glycosphingolipids in polarized hepatic cells.Mol Biol Cell. 2003 Jul;14(7):2689-705. doi: 10.1091/mbc.e02-12-0816. Epub 2003 Apr 4. Mol Biol Cell. 2003. PMID: 12857857 Free PMC article.
Cited by
-
Transcriptomic landscape based on annotated clinical features reveals PLPP2 involvement in lipid raft-mediated proliferation signature of early-stage lung adenocarcinoma.J Exp Clin Cancer Res. 2023 Nov 23;42(1):315. doi: 10.1186/s13046-023-02877-w. J Exp Clin Cancer Res. 2023. PMID: 37996944 Free PMC article.
-
Omega-3 Fatty Acids in Arterial Hypertension: Is There Any Good News?Int J Mol Sci. 2023 May 30;24(11):9520. doi: 10.3390/ijms24119520. Int J Mol Sci. 2023. PMID: 37298468 Free PMC article. Review.
-
Thermoplasmonic Vesicle Fusion Reveals Membrane Phase Segregation of Influenza Spike Proteins.Nano Lett. 2023 Apr 26;23(8):3377-3384. doi: 10.1021/acs.nanolett.3c00371. Epub 2023 Apr 11. Nano Lett. 2023. PMID: 37040311 Free PMC article.
-
Untargeted and Targeted Blood Lipidomic Signature Profile of Gestational Alcohol Exposure.Nutrients. 2023 Mar 15;15(6):1411. doi: 10.3390/nu15061411. Nutrients. 2023. PMID: 36986141 Free PMC article.
-
A review on the role of fatty acids in colorectal cancer progression.Front Pharmacol. 2022 Dec 12;13:1032806. doi: 10.3389/fphar.2022.1032806. eCollection 2022. Front Pharmacol. 2022. PMID: 36578540 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
