Transurethral needle ablation for the treatment of chronic pelvic pain syndrome (category III prostatitis): a randomized, sham-controlled study
- PMID: 12137830
- DOI: 10.1016/s0090-4295(02)01704-1
Transurethral needle ablation for the treatment of chronic pelvic pain syndrome (category III prostatitis): a randomized, sham-controlled study
Abstract
Objectives: To investigate the effectiveness and durability of transurethral needle ablation (TUNA) in the treatment of symptoms of chronic pelvic pain syndrome (CPPS) in a randomized, single-blind, sham-controlled study.
Methods: Thirty-three patients with moderate-to-severe symptoms of CPPS were randomized to either TUNA (n = 25) or urethrocystoscopy as a sham treatment (n = 8). The response to therapy was evaluated 3, 6, and 12 months after treatment using the Prostatitis Symptom Severity Index (PSSI), the International Prostate Symptom Score (IPSS), a visual analogue scale, and prostate volume, prostate-specific antigen, urinary flow, and residual urine volume measurements.
Results: The PSSI decreased in both groups (TUNA group, P <0.001; sham group, P not significant), but no statistically significant difference was detected between them. Similarly, the IPSS decreased in the two groups (TUNA group, P = 0.002; sham group, P = 0.05), but no difference was found between those treated with TUNA and those who underwent sham treatment. Also the quality of life (IPSS-8) was significantly better at 12 months in both groups, but no difference was detected between them. Changes in pain score (visual analogue scale) were not statistically significant. Peak urinary flow rate, residual urine volume, prostate-specific antigen, and prostate volume were not altered in either group.
Conclusions: The efficacy of TUNA in CPPS is comparable to sham treatment, and so cannot be recommended as routine treatment of CPPS.
Comment in
-
Transurethral needle ablation for the treatment of chronic pelvis pain syndrome (category III prostatitis): a randomized, sham-controlled study.J Urol. 2003 Apr;169(4):1617-8. J Urol. 2003. PMID: 12641142 No abstract available.
Similar articles
-
The effect of transurethral needle ablation on symptoms of chronic pelvic pain syndrome--a pilot study.Scand J Urol Nephrol. 2001 Apr;35(2):127-31. Scand J Urol Nephrol. 2001. PMID: 11411655 Clinical Trial.
-
Therapeutic effect of transurethral needle ablation in non-bacterial prostatitis: chronic pelvic pain syndrome type IIIa.Int J Urol. 2004 Feb;11(2):97-102. doi: 10.1111/j.1442-2042.2004.00751.x. Int J Urol. 2004. PMID: 14706013 Clinical Trial.
-
Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study.Urol Int. 2010;84(4):400-6. doi: 10.1159/000302716. Epub 2010 Mar 24. Urol Int. 2010. PMID: 20332612 Clinical Trial.
-
Effect of acupuncture on clinical symptoms and laboratory indicators for chronic prostatitis/chronic pelvic pain syndrome: a systematic review and meta-analysis.Int Urol Nephrol. 2016 Dec;48(12):1977-1991. doi: 10.1007/s11255-016-1403-z. Epub 2016 Sep 2. Int Urol Nephrol. 2016. PMID: 27590134 Review.
-
Contemporary Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome.Eur Urol. 2016 Feb;69(2):286-97. doi: 10.1016/j.eururo.2015.08.061. Epub 2015 Sep 26. Eur Urol. 2016. PMID: 26411805 Review.
Cited by
-
Nonablative transurethral Erbium:YAG laser treatment for chronic prostatitis/chronic pelvic pain syndrome: A prospective comparative study.Neurourol Urodyn. 2021 Jan;40(1):278-285. doi: 10.1002/nau.24551. Epub 2020 Nov 10. Neurourol Urodyn. 2021. PMID: 33170523 Free PMC article.
-
Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome.Cochrane Database Syst Rev. 2018 May 12;5(5):CD012551. doi: 10.1002/14651858.CD012551.pub3. Cochrane Database Syst Rev. 2018. PMID: 29757454 Free PMC article. Review.
-
Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome.Cochrane Database Syst Rev. 2018 Jan 26;1(1):CD012551. doi: 10.1002/14651858.CD012551.pub2. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2018 May 12;5:CD012551. doi: 10.1002/14651858.CD012551.pub3. PMID: 29372565 Free PMC article. Updated. Review.
-
Acupuncture relieves symptoms in chronic prostatitis/chronic pelvic pain syndrome: a randomized, sham-controlled trial.Prostate Cancer Prostatic Dis. 2015 Sep;18(3):249-54. doi: 10.1038/pcan.2015.13. Epub 2015 May 5. Prostate Cancer Prostatic Dis. 2015. PMID: 25939517 Clinical Trial.
-
Management of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): the studies, the evidence, and the impact.World J Urol. 2013 Aug;31(4):747-53. doi: 10.1007/s00345-013-1062-y. Epub 2013 Apr 9. World J Urol. 2013. PMID: 23568442 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical