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Review
. 2002 Sep 19;1572(2-3):294-316.
doi: 10.1016/s0304-4165(02)00316-1.

I-type lectins

Affiliations
Review

I-type lectins

Takashi Angata et al. Biochim Biophys Acta. .

Abstract

The immunoglobulin superfamily is a large category of proteins defined by their structural similarity to immunoglobulins. The majority of these proteins are involved in protein-protein binding as receptors, antibodies or cell adhesion molecules. The I-type lectins are a subset of the immunoglobulin superfamily that are capable of carbohydrate-protein interactions. There are I-type lectins recognizing sialic acids, other sugars and glycosaminoglycans. The occurrence, structure, binding properties and (potential) biological functions of the I-type lectins are reviewed here.

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