ADENOVIRUS-ASSOCIATED DEFECTIVE VIRUS PARTICLES
- PMID: 14325163
- DOI: 10.1126/science.149.3685.754
ADENOVIRUS-ASSOCIATED DEFECTIVE VIRUS PARTICLES
Abstract
Small, DNA-containing particles were separated from preparations of a simian adenovirus. These particles differed antigenically from the adenovirus. Replication of the particles in cell cultures was obtained only when theywere inoculated simultaneously with adenoviruses. This suggests that these adenovirus-associated particles behave as defective viruses.
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