Ischemic heart disease mortality reduction in an arseniasis-endemic area in southwestern Taiwan after a switch in the tap-water supply system
- PMID: 15371236
- DOI: 10.1080/15287390490471451
Ischemic heart disease mortality reduction in an arseniasis-endemic area in southwestern Taiwan after a switch in the tap-water supply system
Abstract
Arsenic has been identified as a major contributing risk factor for development of blackfoot disease (BFD), a unique peripheral vascular disease that was endemic to the southwestern coast of Taiwan, where residents imbibed artesian well water continuing high amounts of arsenic for more than 50 yr. Chronic arsenic exposure was found to be associated with ischemic heart disease (CHD) in a dose-dependent manner. A tap-water supply system was implemented in the early 1960s in the BFD-endemic areas. Artesian well water was no longer used for drinking and cooking after the mid-1970s. The objective of this study was to examine whether CHD-related mortality decreased after consumption of high-arsenic-containing artesian well water ceased and, if so, when the reduction occurred. Standardized mortality ratios (SMRs) for CHD were calculated for the BFD endemic area for the years 1971-2000. Cumulative-sum techniques were used to detect the occurrence of changes in the SMRs. Data show that mortality attributed to CHD declined gradually for approximately 17 to 20 yr following cessation of consumption of high-arsenic artesian well water. Based on the reversibility criterion, the association between arsenic exposure an1rd CHD-related mortality is likely to be causal.
Copyright Taylor & Francis Inc.
Similar articles
-
Does arsenic exposure increase the risk of development of peripheral vascular diseases in humans?J Toxicol Environ Health A. 2006 Oct;69(19):1797-804. doi: 10.1080/15287390600630237. J Toxicol Environ Health A. 2006. PMID: 16905509
-
Bladder cancer mortality reduction after installation of a tap-water supply system in an arsenious-endemic area in southwestern Taiwan.Environ Res. 2005 May;98(1):127-32. doi: 10.1016/j.envres.2004.07.013. Environ Res. 2005. PMID: 15721893
-
Does arsenic exposure increase the risk for liver cancer?J Toxicol Environ Health A. 2004 Oct 8;67(19):1491-500. doi: 10.1080/15287390490486806. J Toxicol Environ Health A. 2004. PMID: 15371225 Review.
-
Lung cancer mortality reduction after installation of tap-water supply system in an arseniasis-endemic area in Southwestern Taiwan.Lung Cancer. 2004 Dec;46(3):265-70. doi: 10.1016/j.lungcan.2004.05.012. Lung Cancer. 2004. PMID: 15541810
-
Blackfoot disease and arsenic: a never-ending story.J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2005;23(1):55-74. doi: 10.1081/GNC-200051860. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2005. PMID: 16291522 Review.
Cited by
-
Human Health Risk Assessment of Artisanal Miners Exposed to Toxic Chemicals in Water and Sediments in the Prestea Huni Valley District of Ghana.Int J Environ Res Public Health. 2016 Jan 18;13(1):139. doi: 10.3390/ijerph13010139. Int J Environ Res Public Health. 2016. PMID: 26797625 Free PMC article.
-
Unusual presentation of arsenic poisoning in a case of celiac disease.Ann Saudi Med. 2015 Mar-Apr;35(2):165-7. doi: 10.5144/0256-4947.2015.165. Ann Saudi Med. 2015. PMID: 26336025 Free PMC article.
-
Cardiovascular disease and arsenic exposure in Inner Mongolia, China: a case control study.Environ Health. 2015 Apr 12;14:35. doi: 10.1186/s12940-015-0022-y. Environ Health. 2015. PMID: 25889926 Free PMC article.
-
Arsenic and lung disease mortality in Bangladeshi adults.Epidemiology. 2014 Jul;25(4):536-43. doi: 10.1097/EDE.0000000000000106. Epidemiology. 2014. PMID: 24802365 Free PMC article.
-
Cardiovascular effects of arsenic: clinical and epidemiological findings.Environ Sci Pollut Res Int. 2014 Jan;21(1):244-51. doi: 10.1007/s11356-013-2113-z. Epub 2013 Sep 10. Environ Sci Pollut Res Int. 2014. PMID: 24019140 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous