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. 2005 Apr 6:6:86.
doi: 10.1186/1471-2105-6-86.

HDBStat!: a platform-independent software suite for statistical analysis of high dimensional biology data

Prinal Trivedi  1 , Jode W Edwards, Jelai Wang, Gary L Gadbury, Vinodh Srinivasasainagendra, Stanislav O Zakharkin, Kyoungmi Kim, Tapan Mehta, Jacob P L Brand, Amit Patki, Grier P Page, David B Allison
Affiliations

HDBStat!: a platform-independent software suite for statistical analysis of high dimensional biology data

Prinal Trivedi et al. BMC Bioinformatics. .

Abstract

Background: Many efforts in microarray data analysis are focused on providing tools and methods for the qualitative analysis of microarray data. HDBStat! (High-Dimensional Biology-Statistics) is a software package designed for analysis of high dimensional biology data such as microarray data. It was initially developed for the analysis of microarray gene expression data, but it can also be used for some applications in proteomics and other aspects of genomics. HDBStat! provides statisticians and biologists a flexible and easy-to-use interface to analyze complex microarray data using a variety of methods for data preprocessing, quality control analysis and hypothesis testing.

Results: Results generated from data preprocessing methods, quality control analysis and hypothesis testing methods are output in the form of Excel CSV tables, graphs and an Html report summarizing data analysis.

Conclusion: HDBStat! is a platform-independent software that is freely available to academic institutions and non-profit organizations. It can be downloaded from our website http://www.soph.uab.edu/ssg_content.asp?id=1164.

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Figures

Figure 1
Figure 1
Data analysis in HDBStat! is divided into four steps – data import, data preprocessing, quality control and hypotheses testing. At each step, user input is required and in return, the results are displayed in the interface and/or output to a file.
Figure 2
Figure 2
Screenshot of gene expression data file in Excel format
Figure 3
Figure 3
Screenshot of chip level information file in Excel format
Figure 4
Figure 4
Deleted residuals graph
Figure 5
Figure 5
Mix-o-matic graph
Figure 6
Figure 6
Power analysis graph
See this image and copyright information in PMC

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