Review
doi: 10.1016/j.cell.2005.06.035.
Sugar-coated regulation of T cells
Affiliations
- PMID: 16009124
- DOI: 10.1016/j.cell.2005.06.035
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Review
Sugar-coated regulation of T cells
Cell.
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Abstract
The human gut is host to hundreds of different species of commensal bacteria that live in peaceful partnership with the host immune system. These commensal bacteria are far from neutral bystanders as they are intimately involved in the development of the immune system. Reporting in this issue of Cell, Kasper and colleagues (Mazmanian et al., 2005) reveal that a bacterial polysaccharide, PSA, produced by the commensal bacterium Bacteroides fragilis directs development of the immune system of the mouse host.
Comment on
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An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system.Cell. 2005 Jul 15;122(1):107-18. doi: 10.1016/j.cell.2005.05.007. Cell. 2005. PMID: 16009137
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