doi: 10.1101/gad.5.11.1935.
Transcription from a TATA-less promoter requires a multisubunit TFIID complex
Affiliations
- PMID: 1657708
- DOI: 10.1101/gad.5.11.1935
Item in Clipboard
Transcription from a TATA-less promoter requires a multisubunit TFIID complex
Genes Dev.
1991 Nov.
Free article
Abstract
In eukaryotes, the TATA box-binding protein (TBP) is responsible for nucleating assembly of the transcription initiation machinery. Here, we report that a TFIID complex containing TBP is essential for transcription even at a promoter that lacks a TATA box. Immunopurification of TFIID reveals that the active species in reconstituting TATA-less transcription is a multisubunit complex consisting of TBP and many TBP-associated factors (TAFs).
Similar articles
-
Holo-TFIID supports transcriptional stimulation by diverse activators and from a TATA-less promoter.Genes Dev. 1992 Oct;6(10):1964-74. doi: 10.1101/gad.6.10.1964. Genes Dev. 1992. PMID: 1398073
-
TATA box-mediated in vitro transcription by RNA polymerase III. Evidence for TATA-binding protein in a polymerase III type complex.J Biol Chem. 1993 Jan 15;268(2):1141-50. J Biol Chem. 1993. PMID: 7678250
-
Core promoter-specific function of a mutant transcription factor TFIID defective in TATA-box binding.Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11864-8. doi: 10.1073/pnas.92.25.11864. Proc Natl Acad Sci U S A. 1995. PMID: 8524864 Free PMC article.
-
Mechanisms of transcriptional activation and repression can both involve TFIID.Philos Trans R Soc Lond B Biol Sci. 1996 Apr 29;351(1339):517-26. doi: 10.1098/rstb.1996.0050. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8735274 Review.
-
Biochemistry and structural biology of transcription factor IID (TFIID).Annu Rev Biochem. 1996;65:769-99. doi: 10.1146/annurev.bi.65.070196.004005. Annu Rev Biochem. 1996. PMID: 8811195 Review.
Cited by
-
Promoter-proximal nucleosomes attenuate RNA polymerase II transcription through TFIID.J Biol Chem. 2023 Jul;299(7):104928. doi: 10.1016/j.jbc.2023.104928. Epub 2023 Jun 15. J Biol Chem. 2023. PMID: 37330174 Free PMC article.
-
Isolation of the Xenopus nrp-1 gene and analysis of its expression following the midblastula transition in injected Xenopus embryos.Dev Growth Differ. 1996 Aug;38(4):439-448. doi: 10.1046/j.1440-169X.1996.t01-3-00012.x. Dev Growth Differ. 1996. PMID: 37281116
-
Stress Triggers Expression of Bovine Herpesvirus 1 Infected Cell Protein 4 (bICP4) RNA during Early Stages of Reactivation from Latency in Pharyngeal Tonsil.J Virol. 2022 Dec 14;96(23):e0101022. doi: 10.1128/jvi.01010-22. Epub 2022 Nov 23. J Virol. 2022. PMID: 36416585 Free PMC article.
-
Cardiac Expression of Esophageal Cancer-Related Gene-4 is Regulated by Sp1 and is a Potential Early Target of Doxorubicin-Induced Cardiotoxicity.Cardiovasc Toxicol. 2022 May;22(5):404-418. doi: 10.1007/s12012-022-09722-0. Epub 2022 Feb 7. Cardiovasc Toxicol. 2022. PMID: 35129819
-
Multidrug efflux transporter ABCG2: expression and regulation.Cell Mol Life Sci. 2021 Nov;78(21-22):6887-6939. doi: 10.1007/s00018-021-03901-y. Epub 2021 Sep 29. Cell Mol Life Sci. 2021. PMID: 34586444 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases
