Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 May;74(5):766-71.

Extinction of experimental Triatoma infestans populations following continuous exposure to dogs wearing deltamethrin-treated collars

Richard Reithinger  1 , Leonardo Ceballos, Raúl Stariolo, Clive R Davies, Ricardo E Gürtler
Affiliations

Extinction of experimental Triatoma infestans populations following continuous exposure to dogs wearing deltamethrin-treated collars

Richard Reithinger et al. Am J Trop Med Hyg. 2006 May.

Abstract

Dogs are domestic reservoir hosts of Trypanosoma cruzi, the etiological agent of Chagas disease. We evaluated the effect of deltamethrin-treated dog collars (DTDCs) over time on the population dynamics of Triatoma infestans, a main T. cruzi vector. Forty founder bugs of mixed life stages were allowed to colonize mud-thatched experimental huts and exposed continuously to either uncollared control dogs (N = 3) or dogs wearing DTDCs (N = 7) for a period of up to 196 days. When compared with bugs exposed to control dogs, bugs exposed to collared dogs were shown to have reduced feeding success (odds ratio [OR] = 0.40; 95% confidence interval [CI], 0.26-0.63; P < 0.001) and lower survival (OR = 0.15; 95% CI, 0.08-0.29; P < 0.001); in fact, all of the bug populations exposed to collared dogs became extinct 77-196 days after study initiation. Bugs exposed to DTDC-wearing dogs were also shown to have a lower fecundity (i.e., number of eggs produced per live female bug: OR = 0.64; 95% CI, 0.51-0.81; P < 0.001) and molting rate to first-instar nymphs (OR = 0.32; 95% CI, 0.13-0.75; P < 0.01) than those bugs exposed to control dogs. DTDCs could represent a novel tool to prevent and control canine and (hence) human Chagas disease.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Proportion of bugs fed or engorged when exposed to dogs fitted with DTDCs or controls. Bugs were scored quantitatively and qualitatively as described in the Materials and Methods section.
Figure 2
Figure 2
Number of live bugs recorded at each time-point after release of 40 founder bugs of different life stages at time 0. Bugs were exposed to either dogs fitted with DTDCs (continuous lines) or controls (broken lines).
Figure 3
Figure 3
Number of eggs and bugs present in huts where bugs were exposed to either control (A) or collared (B) dogs. Total number of eggs observed at time t includes the number of new eggs at time t plus the number of eggs remaining from time t [minus] 1. Number of adult females at time t [minus] 1 is represented by the broken lines; number of first-instar nymphs that developed from eggs is represented by the solid lines.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. World Health Organization. Changing History. Geneva, Switzerland: World Health Organization; 2004. The World Health Report 2004.
    1. Prata A. Clinical and epidemiological aspects of Chagas disease. Lancet Infect Dis. 2001;1:92–100. - PubMed
    1. Schofield CJ, Dias JC. The Southern Cone Initiative against Chagas disease. Adv Parasitol. 1999;42:1–27. - PubMed
    1. Dias JCP, Silveira AC, Schofield CJ. The impact of Chagas disease control in Latin America. Mem Inst Oswaldo Cruz. 2002;97:603–612. - PubMed
    1. Gürtler RE, Petersen RM, Cecere MC, Schweigmann NJ, Chuit R, Gaultieri JM, Wisnivesky-Colli C. Chagas disease in north-west Argentina: risk of domestic reinfestation by Triatoma infestans after a single community-wide application of deltamethrin. Trans R Soc Trop Med Hyg. 1994;88:27–30. - PubMed

Publication types

LinkOut - more resources

-