Review
doi: 10.1016/j.phymed.2007.02.002.
Epub 2007 Mar 7.
Acetylcholinesterase inhibitors from plants
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- PMID: 17346955
- DOI: 10.1016/j.phymed.2007.02.002
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Review
Acetylcholinesterase inhibitors from plants
Phytomedicine.
2007 Apr.
Abstract
Inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown of acetylcholine, is considered as a promising strategy for the treatment of neurological disorders such as Alzheimer's disease, senile dementia, ataxia and myasthenia gravis. A potential source of AChE inhibitors is certainly provided by the abundance of plants in nature. This article aims to provide a comprehensive literature survey of plants that have been tested for AChE inhibitory activity. Numerous phytoconstituents and promising plant species as AChE inhibitors are being reported in this communication.
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