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Comparative Study
. 2010 Aug;33(8):E1-6.
doi: 10.1002/clc.20557.

Gender differences in clinical features and in-hospital outcomes in ST-segment elevation acute myocardial infarction: from the Korean Acute Myocardial Infarction Registry (KAMIR) study

Jong-Seon Park  1 , Young-Jo Kim, Dong-Gu Shin, Myung-Ho Jeong, Young-Keun Ahn, Wook-Sung Chung, Ki-Bae Seung, Chong-Jin Kim, Myeong-Chan Cho, Yang-Soo Jang, Seung-Jung Park, In-Whan Seong, Shung-Chull Chae, Seung-Ho Hur, Dong-Hoon Choi, Taek-Jong Hong; Korean Acute Myocardial Infarction Registry (KAMIR) Group
Collaborators, Affiliations
Comparative Study

Gender differences in clinical features and in-hospital outcomes in ST-segment elevation acute myocardial infarction: from the Korean Acute Myocardial Infarction Registry (KAMIR) study

Jong-Seon Park et al. Clin Cardiol. 2010 Aug.

Abstract

Background: Studies have suggested that women are biologically different and that female gender itself is independently associated with poor clinical outcome after an acute myocardial infarction (AMI).

Hypothesis: We analyzed data from the Korean Acute Myocardial Infarction Registry (KAMIR) to assess gender differences in in-hospital outcomes post ST-segment elevation myocardial infarction (STEMI).

Methods: Between November 2005 and July 2007, 4037 patients who were admitted with STEMI to 41 facilities were registered into the KAMIR database; patients admitted within 72 hours of symptom onset were selected and included in this study.

Results: The proportion of patients who had reperfusion therapy within 12 hours from chest pain onset was lower in women. Women had higher rates of in-hospital mortality (8.6% vs 3.2%, P < .01), noncardiac death (1.5% vs 0.4%, P < .01), cardiac death (7.1% vs 2.8%, P < .01), and stroke (1.2% vs 0.5%, P < .05) than men. Multivariate logistic regression analysis identified age, previous angina, hypertension, a Killip class > or = II, a left ventricular ejection fraction (LVEF) < 40%, and a thrombolysis in myocardial infarction flow (TIMI) grade < or = 3 after angioplasty as independent risk factors for in-hospital death for all patients; however, female gender itself was not an independent risk factor.

Conclusions: The results of this study show that although women have a higher in-hospital mortality than men, female gender itself is not an independent risk factor for in-hospital mortality.

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Figures

Figure 1
Figure 1
The rates of in‐hospital cardiovascular events in women and men. a P < .001 compared with the men. b P < .05 compared with the men
See this image and copyright information in PMC

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