Paint it black (or red, or green): optical and genetic tools illuminate inhibitory contributions to cortical circuit function
- PMID: 20826299
- DOI: 10.1016/j.neuron.2010.08.039
Paint it black (or red, or green): optical and genetic tools illuminate inhibitory contributions to cortical circuit function
Abstract
Visual responses in the cortex are generated by the interactions of feedforward thalamic inputs with local inhibitory and excitatory circuitry, but the exact roles of different cell types in establishing response selectivity are unclear. Two papers in this issue of Neuron (Kerlin et al. and Runyan et al.) combine two-photon imaging with guided electrical recordings to measure orientation tuning in molecularly defined groups of interneuron types.
2010 Elsevier Inc. All rights reserved.
Comment on
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Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex.Neuron. 2010 Sep 9;67(5):847-57. doi: 10.1016/j.neuron.2010.08.006. Neuron. 2010. PMID: 20826315 Free PMC article.
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Broadly tuned response properties of diverse inhibitory neuron subtypes in mouse visual cortex.Neuron. 2010 Sep 9;67(5):858-71. doi: 10.1016/j.neuron.2010.08.002. Neuron. 2010. PMID: 20826316 Free PMC article.
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