Evolution of vertebrate appendicular structures: Insight from genetic and palaeontological data
- PMID: 21337665
- DOI: 10.1002/dvdy.22572
Evolution of vertebrate appendicular structures: Insight from genetic and palaeontological data
Abstract
The new body of evidence from fossils and comparative-developmental analysis of subset of appendicular patterning genes has revealed that limb elements seen in tetrapods are assembled in fish fin over evolutionary time. However, despite of deep homology in basic structure and underlying developmental system, there remains a large morphological gap between distal elements of tetrapod limb and distal fin skeleton of tetrapodomorph fish. Understanding the genetic basis of major transformations in distal-limb morphology is the next challenge for evolutionary developmental biologists. Here by integrating data from fossils, comparative-developmental and genetic studies, models are proposed describing the evolution of cis-regulatory elements as a basis for diversification of appendicular architecture. Instead of emphasizing the subset of developmental genes, for instance Hoxd genes, the focus here is on the significance of elucidating cis-regulatory elements for multiple other key molecular players of limb/fin development and genetic/molecular interactions among them, for a better understanding of the developmental and genetic basis of limb evolution.
Copyright © 2011 Wiley-Liss, Inc.
Similar articles
-
Reconstructing pectoral appendicular muscle anatomy in fossil fish and tetrapods over the fins-to-limbs transition.Biol Rev Camb Philos Soc. 2018 May;93(2):1077-1107. doi: 10.1111/brv.12386. Epub 2017 Nov 10. Biol Rev Camb Philos Soc. 2018. PMID: 29125205 Review.
-
Perspectives on the evolutionary origin of tetrapod limbs.J Exp Zool. 2000 Dec 15;288(4):287-303. doi: 10.1002/1097-010X(20001215)288:4<287::AID-JEZ2>3.0.CO;2-5. J Exp Zool. 2000. PMID: 11144278 Review.
-
New frontiers in the evolution of fin development.J Exp Zool B Mol Dev Evol. 2014 Nov;322(7):540-52. doi: 10.1002/jez.b.22563. Epub 2014 Feb 12. J Exp Zool B Mol Dev Evol. 2014. PMID: 24677573 Review.
-
Tri-phasic expression of posterior Hox genes during development of pectoral fins in zebrafish: implications for the evolution of vertebrate paired appendages.Dev Biol. 2008 Oct 1;322(1):220-33. doi: 10.1016/j.ydbio.2008.06.032. Epub 2008 Jul 3. Dev Biol. 2008. PMID: 18638469
-
The origin of vertebrate limbs.Dev Suppl. 1994:169-80. Dev Suppl. 1994. PMID: 7579518 Review.
Cited by
-
Identification of ancestral gnathostome Gli3 enhancers with activity in mammals.Dev Growth Differ. 2024 Jan;66(1):75-88. doi: 10.1111/dgd.12901. Epub 2023 Dec 20. Dev Growth Differ. 2024. PMID: 37925606
-
The importance of Evolutionary Medicine in developing countries: A case for Pakistan's medical schools.Evol Med Public Health. 2018 Jan 29;2018(1):26-33. doi: 10.1093/emph/eoy004. eCollection 2018. Evol Med Public Health. 2018. PMID: 29492264 Free PMC article. Review.
-
Muscle development in the shark Scyliorhinus canicula: implications for the evolution of the gnathostome head and paired appendage musculature.Front Zool. 2017 Jun 21;14:31. doi: 10.1186/s12983-017-0216-y. eCollection 2017. Front Zool. 2017. PMID: 28649268 Free PMC article.
-
Identification and functional characterization of novel transcriptional enhancers involved in regulating human GLI3 expression during early development.Dev Growth Differ. 2015 Oct;57(8):570-80. doi: 10.1111/dgd.12239. Epub 2015 Oct 14. Dev Growth Differ. 2015. PMID: 26464005 Free PMC article.
-
The Evolution of Bony Vertebrate Enhancers at Odds with Their Coding Sequence Landscape.Genome Biol Evol. 2015 Aug 6;7(8):2333-43. doi: 10.1093/gbe/evv146. Genome Biol Evol. 2015. PMID: 26253316 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous
