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Review
. 1990 Oct;15(10):378-83.
doi: 10.1016/0968-0004(90)90235-4.

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

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Review

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

G Draetta. Trends Biochem Sci. 1990 Oct.

Abstract

cdc2 kinase regulates the progression of eukaryotic cells through the division cycle. Events such as cell growth, DNA replication and mitosis are coordinated through the activation of specific forms of this kinase. Here I discuss our present knowledge of the mechanisms that regulate the activity of cdc2 kinase.

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