Bioaccessibility of total arsenic and arsenic species in seafood as determined by a continuous online leaching method
- PMID: 22307180
- DOI: 10.1007/s00216-012-5774-4
Bioaccessibility of total arsenic and arsenic species in seafood as determined by a continuous online leaching method
Abstract
A continuous leaching method coupled online with inductively coupled plasma mass spectrometry (ICP-MS) detection was used to assess the maximum bioaccessibility of arsenic (As) in seafood samples. The method simulates continuous-flow digestion by successively pumping artificial saliva, gastric and intestinal juices through a mini-column of powdered sample directly connected to the nebuliser of an ICP-MS instrument. The method allows the real-time measurement of As being released by a given reagent. Because the analyte is continuously removed from the system, in contrast to batch methods, the dissolution equilibrium is driven to the right, hence quickly providing information about the worst-case scenario. Following consecutive leaching by the digestive reagents, the leachates were subject to speciation analysis by ion-exchange chromatography with ICP-MS detection to determine the arsenic species released. Finally, the remaining residue from the mini-column was fully digested to verify mass balance. The method was used to determine the bioaccessibility of total As and As species in four certified reference materials and in several real seafood samples. The mass balance was verified in each case. Generally speaking, the non-toxic form was easily released whereas the inorganic forms were poorly bioaccessible.
Similar articles
-
Use of a continuous leaching method to assess the oral bioaccessibility of trace elements in seafood.Food Chem. 2012 Nov 15;135(2):623-33. doi: 10.1016/j.foodchem.2012.03.119. Epub 2012 May 11. Food Chem. 2012. PMID: 22868138
-
Speciation analysis of arsenic in seafood and seaweed: Part II-single laboratory validation of method.Anal Bioanal Chem. 2018 Sep;410(22):5689-5702. doi: 10.1007/s00216-018-0910-4. Epub 2018 Feb 23. Anal Bioanal Chem. 2018. PMID: 29476233
-
Determination of seven arsenic species in seafood by ion exchange chromatography coupled to inductively coupled plasma-mass spectrometry following microwave assisted extraction: method validation and occurrence data.Talanta. 2011 Jan 15;83(3):770-9. doi: 10.1016/j.talanta.2010.10.050. Epub 2010 Nov 5. Talanta. 2011. PMID: 21147319
-
Analytical Methodologies for the Determination of Organoarsenicals in Edible Marine Species: A Review.J Agric Food Chem. 2020 Feb 19;68(7):1910-1934. doi: 10.1021/acs.jafc.9b04525. Epub 2020 Feb 7. J Agric Food Chem. 2020. PMID: 31999115 Free PMC article. Review.
-
Arsenic in the human food chain, biotransformation and toxicology--Review focusing on seafood arsenic.J Trace Elem Med Biol. 2015;31:249-59. doi: 10.1016/j.jtemb.2015.01.010. Epub 2015 Jan 28. J Trace Elem Med Biol. 2015. PMID: 25666158 Review.
Cited by
-
Transformation of arsenic species from seafood consumption during in vitro digestion.Front Nutr. 2023 Oct 12;10:1207732. doi: 10.3389/fnut.2023.1207732. eCollection 2023. Front Nutr. 2023. PMID: 37899842 Free PMC article.
-
On- and off-line analysis by ICP-MS to measure the bioaccessible concentration of elements in PM10 using dynamic versions of the simplified bioaccessibility extraction test.Anal Bioanal Chem. 2023 Jun;415(14):2831-2848. doi: 10.1007/s00216-023-04695-7. Epub 2023 Apr 25. Anal Bioanal Chem. 2023. PMID: 37097303
-
Changes in Arsenic Speciation in Wild Edible Fungi after Different Cooking Processes and Gastrointestinal Digestion.Molecules. 2023 Jan 6;28(2):603. doi: 10.3390/molecules28020603. Molecules. 2023. PMID: 36677657 Free PMC article.
-
Flow-Based Dynamic Approach to Assess Bioaccessible Zinc in Dry Dog Food Samples.Molecules. 2020 Mar 15;25(6):1333. doi: 10.3390/molecules25061333. Molecules. 2020. PMID: 32183441 Free PMC article.
-
Salivary and Gut Microbiomes Play a Significant Role in in Vitro Oral Bioaccessibility, Biotransformation, and Intestinal Absorption of Arsenic from Food.Environ Sci Technol. 2018 Dec 18;52(24):14422-14435. doi: 10.1021/acs.est.8b04457. Epub 2018 Dec 4. Environ Sci Technol. 2018. PMID: 30403856 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials