Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012;91(3):385-95.
doi: 10.1007/s12041-012-0201-3.

DREB1/CBF transcription factors: their structure, function and role in abiotic stress tolerance in plants

M Akhtar  1 , A Jaiswal, G Taj, J P Jaiswal, M I Qureshi, N K Singh
Affiliations
Free article
Review

DREB1/CBF transcription factors: their structure, function and role in abiotic stress tolerance in plants

M Akhtar et al. J Genet. 2012.
Free article

Abstract

Drought, high salinity and low temperature are major abiotic stresses that influence survival, productivity and geographical distribution of many important crops across the globe. Plants respond to these environmental challenges via physiological, cellular and molecular processes, which results in adjusted metabolic and structural alterations. The dehydration-responsiveelement-binding (DREB) protein / C-repeat binding factors (CBFs) belong to APETALA2 (AP2) family transcription factors that bind to DRE/CRT cis-element and regulate the expression of stress-responsive genes. DREB1/CBF genes, therefore, play an important role in increasing stress tolerance in plants and their deployment using transgenic technology seems to be a potential alternative in management of abiotic stresses in crop plants. This review is mainly focussed on the structural characteristics as well as transcriptional regulation of gene expression in response to various abiotic stresses, with particular emphasis on the role of DREB1/CBF regulon in stress-responsive gene expression. The recent progress related to genetic engineering of DREB1/CBF transcription factors in various crops and model plants is also summarized.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):1035-40 - PubMed
    1. Plant Cell Rep. 2006 Dec;25(12):1263-74 - PubMed
    1. Plant Cell. 2002 Aug;14(8):1675-90 - PubMed
    1. Transgenic Res. 2008 Feb;17(1):93-104 - PubMed
    1. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):7076-81 - PubMed

Publication types

LinkOut - more resources

-