Comment
doi: 10.1038/cr.2013.108.
Epub 2013 Aug 13.
Spiking the MERS-coronavirus receptor
Affiliations
- PMID: 23938293
- PMCID: PMC3760624
- DOI: 10.1038/cr.2013.108
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Comment
Spiking the MERS-coronavirus receptor
Cell Res.
2013 Sep.
Abstract
A novel coronavirus, the Middle East respiratory syndrome coronavirus, recently emerged through zoonotic transmission, causing a severe lower respiratory tract infection in humans. In two recent papers, one published in Cell Research, the crystal structure of the viral receptor-binding domain in complex with the host CD26/dipeptidyl peptidase 4 receptor has now been characterized.
Comment on
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Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.Nature. 2013 Aug 8;500(7461):227-31. doi: 10.1038/nature12328. Epub 2013 Jul 7. Nature. 2013. PMID: 23831647 Free PMC article.
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Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4.Cell Res. 2013 Aug;23(8):986-93. doi: 10.1038/cr.2013.92. Epub 2013 Jul 9. Cell Res. 2013. PMID: 23835475 Free PMC article.
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