Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Jan;281(2):583-92.
doi: 10.1111/febs.12530. Epub 2013 Oct 17.

Fifty-five years of enzyme classification: advances and difficulties

Andrew G McDonald  1 , Keith F Tipton
Affiliations
Free article
Review

Fifty-five years of enzyme classification: advances and difficulties

Andrew G McDonald et al. FEBS J. 2014 Jan.
Free article

Abstract

Since the publication of a list of enzymes classified according to the reactions that they catalysed, by Dixon and Webb in 1958, its content and presentation have undergone a number of significant changes. These have been necessitated by new information, as well as the need to improve clarity. The move from printed versions to the online environment, through the ExplorEnz website, has allowed the process of adding newly reported enzymes to be automated and the information content to be enriched. Search and output facilities have also been enhanced. These and the problems attendant on the use of the Enzyme Commission classification system for some groups of enzymes are the subject of this review.

Keywords: EC number; ExplorEnz; IUBMB; IUPAC names; enzyme database.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

LinkOut - more resources

-