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. 2014 Jan;42(Database issue):D38-43.
doi: 10.1093/nar/gkt1082. Epub 2013 Nov 8.

Assembly information services in the European Nucleotide Archive

Affiliations

Assembly information services in the European Nucleotide Archive

Nima Pakseresht et al. Nucleic Acids Res. 2014 Jan.

Abstract

The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the world public domain nucleotide sequence data output. ENA content covers a spectrum of data types including raw reads, assembly data and functional annotation. ENA has faced a dramatic growth in genome assembly submission rates, data volumes and complexity of datasets. This has prompted a broad reworking of assembly submission services, for which we now reach the end of a major programme of work and many enhancements have already been made available over the year to components of the submission service. In this article, we briefly review ENA content and growth over 2013, describe our rapidly developing services for genome assembly information and outline further major developments over the last year.

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Figures

Figure 1.
Figure 1.
The figure presents the number of genome assembly submissions over time.
Figure 2.
Figure 2.
The figure provides a screen shot of an assembly record made visible following a typical search in which the user clicked the ‘Advanced Search’ link from the homepage, checked the ‘assembly’ domain radio button, searched for human genome using organism name ‘human’ and selected GCA_000001405.14 from the listed results. This page provides an assembly description, assembly statistics for all the assembly versions, links to all chromosomes, alternative loci, patches and pseudoautosomal regions in the assembly and references.
Figure 3.
Figure 3.
A result table containing selected fields for Caenorhabditis elegans results from the sequence domain.

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References

    1. Nakamura Y, Cochrane G, Karsch-Mizrachi I. International nucleotide sequence database collaboration. Nucleic Acids Res. 2013;41:D21–D24. - PMC - PubMed
    1. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Wheeler DL. GenBank. Nucleic Acids Res. 2005;33:D34–D38. - PMC - PubMed
    1. Ogasawara O, Mashima J, Kodama Y, Kaminuma E, Nakamura Y, Okubo K, Takagi T. DDBJ new system and service refactoring. Nucleic Acids Res. 2013;41:D25–D29. - PMC - PubMed
    1. Kozomara A, Griffiths-Jones S. miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res. 2011;39:D152–D157. - PMC - PubMed
    1. Andersen ES, Rosenblad MA, Larsen N, Westergaard JC, Burks J, Wower IK, Wower J, Gorodkin J, Samuelsson T, Zwieb C. The tmRDB and SRPDB resources. Nucleic Acids Res. 2006;34:D163–D168. - PMC - PubMed

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