Measles virus
- PMID: 25483511
- PMCID: PMC4514292
- DOI: 10.4161/hv.34298
Measles virus
Abstract
Measles was an inevitable infection during the human development with substantial degree of morbidity and mortality. The severity of measles virus (MV) infection was largely contained by the development of a live attenuated vaccine that was introduced into the vaccination programs. However, all efforts to eradicate the disease failed and continued to annually result in significant deaths. The development of molecular biology techniques allowed the rescue of MV from cDNA that enabled important insights into a variety of aspects of the biology of the virus and its pathogenesis. Subsequently these technologies facilitated the development of novel vaccine candidates that induce immunity against measles and other pathogens. Based on the promising prospective, the use of MV as a recombinant vaccine and a therapeutic vector is addressed.
Keywords: SSPE; live viral vaccine; measles; pathogenesis; recombinant vaccines; vaccine; viral vectors.
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References
-
- Krugman S, Katz SL, Gershon AA, Wilfert C. Measles. In: Infectious diseases of Children 1985; 8th edn. Mosby, St Louis, 152-166.
-
- Otri AM, Singh AD, Dua HS.. Cover illustration. Abu Bakr Razi. [BMJ Group]Br J Ophthalmol 2008; 92:1324; PMID: 18815419 - PubMed
-
- Clements CJ, Cutts FT.. The epidemiology of measles: thirty years of vaccination. Curr Top Microbiol Immunol 1995; 191:13 - 33; http://dx.doi.org/10.1007/978-3-642-78621-1_2; PMID: 7789156 - DOI - PubMed
-
- Chen SSP, Fennelly G, Burnett M, Domachowske J, Dyne PL, Elston DM, et al. “Measles” 2014; In Steele, RW. Medscape Reference. WebMD. Retrieved 23 March 2014
-
- Risk of infection East and Southwest Asia (Report). Occucare International. May 16, 2012; p. 6
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