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. 1985 Jan;313(6000):277-84.
doi: 10.1038/313277a0.

Complete nucleotide sequence of the AIDS virus, HTLV-III

Complete nucleotide sequence of the AIDS virus, HTLV-III

L Ratner et al. Nature. 1985 Jan.

Abstract

The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral DNAs each have four long open reading frames, the first two corresponding to the gag and pol genes. The fourth open reading frame encodes two functional polypeptides, a large precursor of the major envelope glycoprotein and a smaller protein derived from the 3'-terminus long open reading frame analogous to the long open reading frame (lor) product of HTLV-I and -II.

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