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Review
. 2015 Mar 19:11:435-48.
doi: 10.2147/TCRM.S51168. eCollection 2015.

Epidemiology of Japanese encephalitis: past, present, and future prospects

Affiliations
Review

Epidemiology of Japanese encephalitis: past, present, and future prospects

Huanyu Wang et al. Ther Clin Risk Manag. .

Abstract

Japanese encephalitis (JE) is one of severe viral encephalitis that affects individuals in Asia, western Pacific countries, and northern Australia. Although 67,900 JE cases have been estimated among 24 JE epidemic countries annually, only 10,426 have been reported in 2011. With the establishment of JE surveillance and vaccine use in some countries, the JE incidence rate has decreased; however, serious outbreaks still occur. Understanding JE epidemics and identifying the circulating JE virus genotypes will improve JE prevention and control. This review summarizes the current epidemiology data in these countries.

Keywords: Japanese encephalitis; Japanese encephalitis virus; acute encephalitis syndrome.

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Figures

Figure 1
Figure 1
Global distribution of Japanese encephalitis (JE) infection countries and risk areas. Notes: ■Japanese encephalitis risk countries that the epidemiological pattern of JE is epidemic; ■Japanese encephalitis risk countries that the epidemiological pattern of JE is endemic.

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References

    1. Erlanger TE, Weiss S, Keiser J, Utzinger J, Wiedenmayer K. Past, present, and future of Japanese encephalitis. Emerg Infect Dis. 2009;15(1):1–7. - PMC - PubMed
    1. Japanese encephalitis surveillance and immunization – Asia and the Western pacific, 2012. MMWR Morb Mortal Wkly Rep. 2013;62(33):658–662. - PMC - PubMed
    1. Campbell GL, Hills SL, Fischer M, et al. Estimated global incidence of Japanese encephalitis: a systematic review. Bull World Health Organ. 2011;89(10):766–774. 774A. - PMC - PubMed
    1. Solomon T. Flavivirus encephalitis. N Engl J Med. 2004;351(4):370–378. - PubMed
    1. Chambers TJ, Hahn CS, Galler R, Rice CM. Flavivirus genome organization, expression, and replication. Annu Rev Microbiol. 1990;44:649–688. - PubMed

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