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Review
. 2017 Feb;18(2):87-100.
doi: 10.1038/nrg.2016.133. Epub 2016 Nov 14.

Making sense of genomic islands of differentiation in light of speciation

Jochen B W Wolf  1   2 , Hans Ellegren  1
Affiliations
Review

Making sense of genomic islands of differentiation in light of speciation

Jochen B W Wolf et al. Nat Rev Genet. 2017 Feb.

Abstract

As populations diverge, genetic differences accumulate across the genome. Spurred by rapid developments in sequencing technology, genome-wide population surveys of natural populations promise insights into the evolutionary processes and the genetic basis underlying speciation. Although genomic regions of elevated differentiation are the focus of searches for 'speciation genes', there is an increasing realization that such genomic signatures can also arise by alternative processes that are not related to population divergence, such as linked selection. In this Review, we explore methodological trends in speciation genomic studies, highlight the difficulty in separating processes related to speciation from those emerging from genome-wide properties that are not related to reproductive isolation, and provide a set of suggestions for future work in this area.

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References

    1. Genetics. 1989 Nov;123(3):585-95 - PubMed
    1. Annu Rev Ecol Evol Syst. 2008 Dec 1;39:21-42 - PubMed
    1. Genome Res. 2015 Nov;25(11):1656-65 - PubMed
    1. Theor Popul Biol. 1975 Apr;7(2):256-76 - PubMed
    1. Nat Commun. 2015 Jun 04;6:7330 - PubMed

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