Review
doi: 10.1002/jcp.25778.
Epub 2017 Mar 31.
Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?
Affiliations
- PMID: 28059453
- DOI: 10.1002/jcp.25778
Item in Clipboard
Review
Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?
J Cell Physiol.
2018 Feb.
Abstract
Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities. Novel animal and human studies indicate that curcumin can affect different immune cells, such as various T lymphocyte subsets, macrophages, dendritic cells, B lymphocytes and natural killer cells, which results in decreasing severity of various diseases with immunological etiology. The present review provides a comprehensive overview of the effects of curcumin on different immune cells and immune system-related diseases.
Keywords: autoimmune disease; curcumin; immune system; inflammation.
© 2017 Wiley Periodicals, Inc.
Similar articles
-
Curcumin: a modulator of inflammatory signaling pathways in the immune system.Inflammopharmacology. 2019 Oct;27(5):885-900. doi: 10.1007/s10787-019-00607-3. Epub 2019 May 28. Inflammopharmacology. 2019. PMID: 31140036 Review.
-
One Molecule, Many Targets and Numerous Effects: The Pleiotropy of Curcumin Lies in its Chemical Structure.Curr Pharm Des. 2018;24(19):2129-2136. doi: 10.2174/1381612824666180522111036. Curr Pharm Des. 2018. PMID: 29788873 Review.
-
Immune modulatory effects of statins.Immunology. 2018 May;154(1):69-75. doi: 10.1111/imm.12902. Epub 2018 Feb 20. Immunology. 2018. PMID: 29392731 Free PMC article. Review.
-
Curcumin targets in inflammation and cancer.Endocr Metab Immune Disord Drug Targets. 2015;15(2):88-96. doi: 10.2174/1871530315666150316120458. Endocr Metab Immune Disord Drug Targets. 2015. PMID: 25772169 Review.
-
Treating atherosclerosis with regulatory T cells.Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):280-7. doi: 10.1161/ATVBAHA.114.303568. Epub 2014 Nov 20. Arterioscler Thromb Vasc Biol. 2015. PMID: 25414253 Free PMC article. Review.
Cited by
-
Immunomodulatory effects of curcumin on macrophage polarization in rheumatoid arthritis.Front Pharmacol. 2024 Feb 28;15:1369337. doi: 10.3389/fphar.2024.1369337. eCollection 2024. Front Pharmacol. 2024. PMID: 38487171 Free PMC article. Review.
-
A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease.Inflammopharmacology. 2023 Jun;31(3):1095-1105. doi: 10.1007/s10787-023-01140-0. Epub 2023 Feb 9. Inflammopharmacology. 2023. PMID: 36757584 Review.
-
Antibacterial properties of an acrylic resin containing curcumin nanoparticles: An in vitro study.J Dent Res Dent Clin Dent Prospects. 2022 Summer;16(3):190-195. doi: 10.34172/joddd.2022.032. Epub 2022 Nov 15. J Dent Res Dent Clin Dent Prospects. 2022. PMID: 36704184 Free PMC article.
-
Neem Oil or Almond Oil Nanoemulsions for Vitamin E Delivery: From Structural Evaluation to in vivo Assessment of Antioxidant and Anti-Inflammatory Activity.Int J Nanomedicine. 2022 Dec 20;17:6447-6465. doi: 10.2147/IJN.S376750. eCollection 2022. Int J Nanomedicine. 2022. PMID: 36573206 Free PMC article.
-
Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling.World J Gastroenterol. 2022 Oct 28;28(40):5865-5880. doi: 10.3748/wjg.v28.i40.5865. World J Gastroenterol. 2022. PMID: 36353208 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
