Factors associated with uterine fibroid in Ghanaian women undergoing pelvic scans with suspected uterine fibroid

doi:10.1186/s40738-016-0022-9

. 2016 May 1:2:9.

doi: 10.1186/s40738-016-0022-9. eCollection 2016.

Factors associated with uterine fibroid in Ghanaian women undergoing pelvic scans with suspected uterine fibroid

Benjamin Dabo Sarkodie¹, Benard Ohene Botwe², David Nana Adjei³, Eric Ofori²

Affiliations

¹ Univeristy of Ghana, School of Medicine and Dentistry, P. O. Box GP 4236, Accra, Ghana.
² Department of Radiography, University Ghana School of Biomedical and Allied Health Sciences, College of Health Sciences, P.O. Box KB 143, Korle Bu, Accra, Ghana.
³ Department of Medical Laboratory Sciences, University Ghana School of Biomedical and Allied Health Sciences, College of Health Sciences, P.O. Box KB 143, Korle Bu, Accra, Ghana.

PMID: 28620536
PMCID: PMC5424414
DOI: 10.1186/s40738-016-0022-9

Factors associated with uterine fibroid in Ghanaian women undergoing pelvic scans with suspected uterine fibroid

Benjamin Dabo Sarkodie et al. Fertil Res Pract. 2016.

. 2016 May 1:2:9.

doi: 10.1186/s40738-016-0022-9. eCollection 2016.

Authors

Benjamin Dabo Sarkodie¹, Benard Ohene Botwe², David Nana Adjei³, Eric Ofori²

Affiliations

¹ Univeristy of Ghana, School of Medicine and Dentistry, P. O. Box GP 4236, Accra, Ghana.
² Department of Radiography, University Ghana School of Biomedical and Allied Health Sciences, College of Health Sciences, P.O. Box KB 143, Korle Bu, Accra, Ghana.
³ Department of Medical Laboratory Sciences, University Ghana School of Biomedical and Allied Health Sciences, College of Health Sciences, P.O. Box KB 143, Korle Bu, Accra, Ghana.

PMID: 28620536
PMCID: PMC5424414
DOI: 10.1186/s40738-016-0022-9

Abstract

Background: Uterine fibroids are the most common benign tumours affecting premenopausal women and are often associated with considerable hospitalization and morbidity. Literature shows virtually no study concerning the quantification of the main factors associated with uterine fibroids in Ghanaian women. The purpose of this study was to assess the main factors associated with uterine fibroid among Ghanaian women presenting for ultrasound.

Method: A prospective cross-sectional study design was employed in this study. A total of two hundred and forty-four (244) women were consecutively evaluated from November 2011 to February 2012 using a 2-5 MHz curvilinear probe of Philips HD3 ultrasound machines at three centres in Accra using a trans-abdominal pelvic approach. Data was analysed with (SPSS) version 20.0 for windows, 2010; Chicago. The Pearson's Chi-square test was used to determine associations between selected demographic and gynaecological characteristics and uterine fibroid appearance. All tests were two-tailed and p-value of less than 0.05 was interpreted as significant.

Results: The range, mean and standard deviation (SD) of the patients' age were 14-54 years, 31.89 years and ± 7.92 respectively. Factors that associated significantly with uterine fibroid in Ghanaian women included obesity (X² = 17.3, p-value = 0.001), participant's age range (X² = 47.4, p-value = 0.001), parity (X² = -10.169, p-value = 0.001), and age at last delivery (X² = 34.579, p-value = 0.001).

Conclusion: Uterine fibroid was mainly associated with women of older age group of the reproductive age than the younger age categories and also associated more with women with without children compared to those with more children. Moreover, it associated more with obese patients and patient with late age at last delivery.

Keywords: Associated factors; Ghana; Ultrasound; Uterine fibroid.

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Figures

**Fig. 1**
Confirmed fibroid distribution among the ethnic groups

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References

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1. Levy B, Mukhejee T, Hirschhorn K. Molecular cytogenetic analysis of uterine leiomyomas and leimyosarcoma by comparative genomic hybridization. Cancer Cytogenet. 2000;12:1–8. doi: 10.1016/S0165-4608(00)00225-9. - DOI - PubMed
1. Viswanathan M, Hartmann K, McKoy N, et al. Management of Uterine Fibroids: An update of evidence. Agency for Healthcare Research and Quality (AHRQ): Summary, Evidence Report/Technology Assessment 2007; Number 154. AHRQ Publication No. 01-E051.
1. Jennelle CH, Bradley JQ, Mark AR, Elizabeth AS, Paola Dal C, Cynthia CM. Molecular and Cytogenetic Characterization of PlexiformLeiomyomata Provide Further Evidence for Genetic Heterogeneity Underlying Uterine Fibroids. Am J Pathol. 2008;172:1403–1410. doi: 10.2353/ajpath.2008.071102. - DOI - PMC - PubMed

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[1] Goodwin SC, Spices JB, Worthington-Kirsch R, Peterson E, Prong LS, Myers ER. Uterine Artery Embplization For Treatment of leiomyomata: Long Term Out comes From Fibroid Registry. Obset Gynecol. 2008;111:22–33. doi: 10.1097/01.AOG.0000296526.71749.c9. - DOI - PubMed

[2] Goodwin SC, Spices JB, Worthington-Kirsch R, Peterson E, Prong LS, Myers ER. Uterine Artery Embplization For Treatment of leiomyomata: Long Term Out comes From Fibroid Registry. Obset Gynecol. 2008;111:22–33. doi: 10.1097/01.AOG.0000296526.71749.c9. - DOI - PubMed

[3] Fledderjohann JJ. “Zero is not good for me”: implications of infertility in Ghana. Hum Reprod. 2012;27(5):1383–1390. doi: 10.1093/humrep/des035. - DOI - PubMed

[4] Fledderjohann JJ. “Zero is not good for me”: implications of infertility in Ghana. Hum Reprod. 2012;27(5):1383–1390. doi: 10.1093/humrep/des035. - DOI - PubMed

[5] Levy B, Mukhejee T, Hirschhorn K. Molecular cytogenetic analysis of uterine leiomyomas and leimyosarcoma by comparative genomic hybridization. Cancer Cytogenet. 2000;12:1–8. doi: 10.1016/S0165-4608(00)00225-9. - DOI - PubMed

[6] Levy B, Mukhejee T, Hirschhorn K. Molecular cytogenetic analysis of uterine leiomyomas and leimyosarcoma by comparative genomic hybridization. Cancer Cytogenet. 2000;12:1–8. doi: 10.1016/S0165-4608(00)00225-9. - DOI - PubMed

[7] Viswanathan M, Hartmann K, McKoy N, et al. Management of Uterine Fibroids: An update of evidence. Agency for Healthcare Research and Quality (AHRQ): Summary, Evidence Report/Technology Assessment 2007; Number 154. AHRQ Publication No. 01-E051.

[8] Viswanathan M, Hartmann K, McKoy N, et al. Management of Uterine Fibroids: An update of evidence. Agency for Healthcare Research and Quality (AHRQ): Summary, Evidence Report/Technology Assessment 2007; Number 154. AHRQ Publication No. 01-E051.

[9] Jennelle CH, Bradley JQ, Mark AR, Elizabeth AS, Paola Dal C, Cynthia CM. Molecular and Cytogenetic Characterization of PlexiformLeiomyomata Provide Further Evidence for Genetic Heterogeneity Underlying Uterine Fibroids. Am J Pathol. 2008;172:1403–1410. doi: 10.2353/ajpath.2008.071102. - DOI - PMC - PubMed

[10] Jennelle CH, Bradley JQ, Mark AR, Elizabeth AS, Paola Dal C, Cynthia CM. Molecular and Cytogenetic Characterization of PlexiformLeiomyomata Provide Further Evidence for Genetic Heterogeneity Underlying Uterine Fibroids. Am J Pathol. 2008;172:1403–1410. doi: 10.2353/ajpath.2008.071102. - DOI - PMC - PubMed

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Factors associated with uterine fibroid in Ghanaian women undergoing pelvic scans with suspected uterine fibroid

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Factors associated with uterine fibroid in Ghanaian women undergoing pelvic scans with suspected uterine fibroid

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