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Review
. 2018 Jan 1;17(1):64-76.
doi: 10.1093/bfgp/elx019.

A brief review of single-cell transcriptomic technologies

Tomer Kalisky, Sarit Oriel, Tali Hana Bar-Lev, Nissim Ben-Haim, Ariel Trink, Yishay Wineberg, Itamar Kanter, Shlomit Gilad, Saumyadipta Pyne
Review

A brief review of single-cell transcriptomic technologies

Tomer Kalisky et al. Brief Funct Genomics. .

Abstract

In recent years, there has been an effort to develop new technologies for measuring gene expression and sequence information from thousands of individual cells. Large data sets that were obtained using these 'single cell' technologies have allowed scientists to address fundamental questions in biomedicine ranging from stems cells and development to cancer and immunology. Here, we provide a brief review of recent developments in single-cell technology. Our intention is to provide a quick background for newcomers to the field as well as a deeper description of some of the leading technologies to date.

Keywords: RNA sequencing; genomics; single-cell technologies.

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