Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial
- PMID: 29992110
- PMCID: PMC6035493
- DOI: 10.1016/j.jtcme.2017.07.005
Impact of green tea extract on serum lipid of postmenopausal women: A randomized controlled trial
Abstract
Background: This study aimed to evaluate the impact of green tea extract on serum lipid level in postmenopausal women.
Method: In this randomized controlled trial 100 postmenopausal women with an abnormality in at least one lipid profile were recruited and randomly assigned to one of the two groups: green tea extract (n = 50) and control group (n = 50). The intervention group received two capsules (400 mg) of green tea extract two times daily; the control group received a placebo for 4 weeks. The serum level of the lipid profile (total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride, and fasting blood sugar) was measured at baseline and 4 weeks after intervention.
Results: In total, 79 women completed the study. The mean total cholesterol in the green tea group was significantly decreased after 4 weeks of intervention (mean difference -18.1 vs. -5 mg/dL in the green tea and placebo groups, p < 0.04). The triglyceride and LDL also decreased significantly in the green tea group compared to the control group (p = 0.002 and p = 0.04 respectively). The level of HDL and fasting blood sugar did not change within the group and between groups.
Conclusion: Green tea extract is cost-effective way to decrease lipid profile in postmenopausal women without major side effects. Using this herb is recommended in women who have slight lipid profile abnormalities.
Keywords: Green tea extract; High density lipoprotein; Low density lipoprotein; Total cholesterol; Triglyceride.
Figures
Similar articles
-
Effect of green tea consumption on blood lipids: a systematic review and meta-analysis of randomized controlled trials.Nutr J. 2020 May 20;19(1):48. doi: 10.1186/s12937-020-00557-5. Nutr J. 2020. PMID: 32434539 Free PMC article. Review.
-
Effects of green tea extract on overweight and obese women with high levels of low density-lipoprotein-cholesterol (LDL-C): a randomised, double-blind, and cross-over placebo-controlled clinical trial.BMC Complement Altern Med. 2018 Nov 6;18(1):294. doi: 10.1186/s12906-018-2355-x. BMC Complement Altern Med. 2018. PMID: 30400924 Free PMC article. Clinical Trial.
-
A comparative study of the effect of green tea and sour tea on blood pressure and lipid profile in healthy adult men.ARYA Atheroscler. 2017 May;13(3):109-116. ARYA Atheroscler. 2017. PMID: 29147120 Free PMC article.
-
Green tea catechins decrease total and low-density lipoprotein cholesterol: a systematic review and meta-analysis.J Am Diet Assoc. 2011 Nov;111(11):1720-9. doi: 10.1016/j.jada.2011.08.009. J Am Diet Assoc. 2011. PMID: 22027055 Review.
-
Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial.Arch Intern Med. 2003 Jun 23;163(12):1448-53. doi: 10.1001/archinte.163.12.1448. Arch Intern Med. 2003. PMID: 12824094 Clinical Trial.
Cited by
-
Green Tea Extract has a Protective Effect on Leptin and Lipid Profile Levels Due to the Induction of Depot Medroxyprogesterone Acetate.Med Arch. 2023;77(3):173-177. doi: 10.5455/medarh.2023.77.173-177. Med Arch. 2023. PMID: 37700918 Free PMC article.
-
Green Tea and Benign Gynecologic Disorders: A New Trick for An Old Beverage?Nutrients. 2023 Mar 16;15(6):1439. doi: 10.3390/nu15061439. Nutrients. 2023. PMID: 36986169 Free PMC article. Review.
-
The effects of green tea supplementation on cardiovascular risk factors: A systematic review and meta-analysis.Front Nutr. 2023 Jan 10;9:1084455. doi: 10.3389/fnut.2022.1084455. eCollection 2022. Front Nutr. 2023. PMID: 36704803 Free PMC article. Review.
-
A novel phenolic formulation for treating hepatic and peripheral insulin resistance by regulating GLUT4-mediated glucose uptake.J Tradit Complement Med. 2021 Aug 8;12(2):195-205. doi: 10.1016/j.jtcme.2021.08.004. eCollection 2022 Mar. J Tradit Complement Med. 2021. PMID: 35528476 Free PMC article.
-
Prophylactic effect of Trigonella foenum-graecum L. seed extract on inflammatory markers and histopathological changes in high-fat-fed ovariectomized rats.J Tradit Complement Med. 2021 Jul 18;12(2):131-140. doi: 10.1016/j.jtcme.2021.07.003. eCollection 2022 Mar. J Tradit Complement Med. 2021. PMID: 35528469 Free PMC article.
References
-
- Taffe J.R., Dennerstein L. Menstrual patterns leading to the final menstrual period. Menopause. 2002;9:32. - PubMed
-
- Greendale G.A., Hogan P., Kritz-Silverstein D. Age at menopause in women participating in the postmenopausal estrogen/progestins interventions (PEPI) trial: an example of bias introduced by selection criteria. Menopause. 1995;2:27–34.
-
- Rosano G.M., Vitale C., Marazzi G. Menopause and cardiovascular disease: the evidence. Climacteric. 2007 Feb;10(1):19–24. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources