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Review

Ustekinumab

No authors listed
In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.
.
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Review

Ustekinumab

No authors listed.
Free Books & Documents

Excerpt

Ustekinumab is usually either not detectable in breastmilk or detectable at very low levels in breastmilk. It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal.[1] Many infants have been safely breastfed during maternal treatment with ustekinumab. If ustekinumab is required by the mother, it is not a reason to discontinue breastfeeding and some experts and professional organizations consider it acceptable during breastfeeding.[2-8] Waiting for at least 2 weeks postpartum to resume therapy may minimize transfer to the infant.[9]

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References

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    1. Götestam Skorpen C, Hoeltzenbein M, Tincani A, et al. The EULAR points to consider for use of antirheumatic drugs before pregnancy, and during pregnancy and lactation. Ann Rheum Dis 2016;75:795-810. - PubMed
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    1. Mahadevan U, Robinson C, Bernasko N, et al. Inflammatory bowel disease in pregnancy clinical care pathway: A report from the American Gastroenterological Association IBD Parenthood Project Working Group. Gastroenterology 2019;156:1508-24. - PubMed

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