Detection of distinct MERS-Coronavirus strains in dromedary camels from Kenya, 2017

doi:10.1038/s41426-018-0193-z

. 2018 Nov 28;7(1):195.

doi: 10.1038/s41426-018-0193-z.

Detection of distinct MERS-Coronavirus strains in dromedary camels from Kenya, 2017

Stella Kiambi¹, Victor M Corman^{2

3}, Rina Sitawa⁴, Jane Githinji⁴, James Ngoci⁴, Abdullahi S Ozomata⁵, Emma Gardner¹, Sophie von Dobschuetz¹, Subhash Morzaria¹, Joshua Kimutai¹, Simon Schroeder², Obadiah Njagi⁴, Piers Simpkin¹, Gabriel Rugalema¹, Zelalem Tadesse¹, Juan Lubroth¹, Yilma Makonnen¹, Christian Drosten^{2

3}, Marcel A Müller^{6

7}, Folorunso O Fasina¹

Affiliations

¹ Food and Agriculture Organization of the United Nations (FAO), Rome, Italy.
² Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin, Germany.
³ German Centre for Infection Research, associated partner Charité, Berlin, Germany.
⁴ Directorate of Veterinary Services, Nairobi, Kenya.
⁵ University of Nairobi, Nairobi, Kenya.
⁶ Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin, Germany. marcel.mueller@charite.de.
⁷ German Centre for Infection Research, associated partner Charité, Berlin, Germany. marcel.mueller@charite.de.

PMID: 30482895
PMCID: PMC6258726
DOI: 10.1038/s41426-018-0193-z

Detection of distinct MERS-Coronavirus strains in dromedary camels from Kenya, 2017

Stella Kiambi et al. Emerg Microbes Infect. 2018.

. 2018 Nov 28;7(1):195.

doi: 10.1038/s41426-018-0193-z.

Authors

Affiliations

¹ Food and Agriculture Organization of the United Nations (FAO), Rome, Italy.
² Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin, Germany.
³ German Centre for Infection Research, associated partner Charité, Berlin, Germany.
⁴ Directorate of Veterinary Services, Nairobi, Kenya.
⁵ University of Nairobi, Nairobi, Kenya.
⁶ Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin, Germany. marcel.mueller@charite.de.
⁷ German Centre for Infection Research, associated partner Charité, Berlin, Germany. marcel.mueller@charite.de.

PMID: 30482895
PMCID: PMC6258726
DOI: 10.1038/s41426-018-0193-z

No abstract available

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Figures

**Fig. 1. Maximum-likelihood phylogeny of the complete coding sequences of representatives of MERS-CoV and the two sequences from this study (highlighted in red).**
Virus designations include GenBank accession numbers and strain names. Black circles at nodes indicate bootstrap supports of >90% and white circles>75% (500 replicates). The top clade “8x Nigeria/2016” was collapsed for graphical reasons and contains eight MERS-CoV sequences (Acc. No. MG923474-81) from dromedaries in Nigeria in 2016

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References

1. Zaki Ali M., van Boheemen Sander, Bestebroer Theo M., Osterhaus Albert D.M.E., Fouchier Ron A.M. Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia. New England Journal of Medicine. 2012;367(19):1814–1820. doi: 10.1056/NEJMoa1211721. - DOI - PubMed
1. WHO. Middle East respiratory syndrome coronavirus (MERS-CoV). http://www.who.int/emergencies/mers-cov/en/. Accessed 28 September 2018 (2018).
1. Younan M, Bornstein S, Gluecks IV. MERS and the dromedary camel trade between Africa and the Middle East. Trop. Anim. Health Prod. 2016;48:1277–1282. doi: 10.1007/s11250-016-1089-3. - DOI - PMC - PubMed
1. Chu DKW, et al. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc. Natl Acad. Sci. USA. 2018;A115:3144–3149. doi: 10.1073/pnas.1718769115. - DOI - PMC - PubMed
1. Ali, M. et al. Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016. Euro Surveill. 22. 10.2807/1560-7917.ES.2017.22.11.30487 (2017). - PMC - PubMed

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[1] Zaki Ali M., van Boheemen Sander, Bestebroer Theo M., Osterhaus Albert D.M.E., Fouchier Ron A.M. Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia. New England Journal of Medicine. 2012;367(19):1814–1820. doi: 10.1056/NEJMoa1211721. - DOI - PubMed

[2] Zaki Ali M., van Boheemen Sander, Bestebroer Theo M., Osterhaus Albert D.M.E., Fouchier Ron A.M. Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia. New England Journal of Medicine. 2012;367(19):1814–1820. doi: 10.1056/NEJMoa1211721. - DOI - PubMed

[3] WHO. Middle East respiratory syndrome coronavirus (MERS-CoV). http://www.who.int/emergencies/mers-cov/en/. Accessed 28 September 2018 (2018).

[4] WHO. Middle East respiratory syndrome coronavirus (MERS-CoV). http://www.who.int/emergencies/mers-cov/en/. Accessed 28 September 2018 (2018).

[5] Younan M, Bornstein S, Gluecks IV. MERS and the dromedary camel trade between Africa and the Middle East. Trop. Anim. Health Prod. 2016;48:1277–1282. doi: 10.1007/s11250-016-1089-3. - DOI - PMC - PubMed

[6] Younan M, Bornstein S, Gluecks IV. MERS and the dromedary camel trade between Africa and the Middle East. Trop. Anim. Health Prod. 2016;48:1277–1282. doi: 10.1007/s11250-016-1089-3. - DOI - PMC - PubMed

[7] Chu DKW, et al. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc. Natl Acad. Sci. USA. 2018;A115:3144–3149. doi: 10.1073/pnas.1718769115. - DOI - PMC - PubMed

[8] Chu DKW, et al. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc. Natl Acad. Sci. USA. 2018;A115:3144–3149. doi: 10.1073/pnas.1718769115. - DOI - PMC - PubMed

[9] Ali, M. et al. Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016. Euro Surveill. 22. 10.2807/1560-7917.ES.2017.22.11.30487 (2017). - PMC - PubMed

[10] Ali, M. et al. Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016. Euro Surveill. 22. 10.2807/1560-7917.ES.2017.22.11.30487 (2017). - PMC - PubMed

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Detection of distinct MERS-Coronavirus strains in dromedary camels from Kenya, 2017

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Detection of distinct MERS-Coronavirus strains in dromedary camels from Kenya, 2017

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