Site-Selective 1,2-Dicarbofunctionalization of Vinyl Boronates through Dual Catalysis
- PMID: 31910307
- DOI: 10.1002/anie.201916279
Site-Selective 1,2-Dicarbofunctionalization of Vinyl Boronates through Dual Catalysis
Abstract
A modular, site-selective 1,2-dicarbofunctionalization of vinyl boronates with organic halides through dual catalysis is described. This reaction proceeds under mild conditions and is characterized by excellent chemo- and regioselectivity. It thus represents a complementary new technique for preparing densely functionalized alkyl boron architectures from simple and accessible precursors.
Keywords: Ni; dicarbofunctionalization; dual catalysis; homogeneous catalysis; radical reactions.
© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
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