Associations between fine particulate matter constituents and daily cardiovascular mortality in Shanghai, China

doi:10.1016/j.ecoenv.2019.110154

. 2020 Mar 15:191:110154.

doi: 10.1016/j.ecoenv.2019.110154. Epub 2020 Jan 15.

Associations between fine particulate matter constituents and daily cardiovascular mortality in Shanghai, China

Cuiping Wang¹, Lipeng Hao², Cong Liu¹, Renjie Chen¹, Weidong Wang¹, Yichen Chen², Yining Yang³, Xia Meng⁴, Qingyan Fu⁵, Zhekang Ying⁶, Haidong Kan¹

Affiliations

¹ School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, 200032, China.
² Shanghai Pudong New Area Center for Disease Control and Prevention, Fudan University Pudong Institute of Preventive Medicine, Shanghai, 200136, China.
³ Beijing No.171 High School, Beijing, 100013, China.
⁴ School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, 200032, China. Electronic address: mengxxia@gmail.com.
⁵ Shanghai Environmental Monitoring Center, Shanghai, 200235, China. Electronic address: qingyanf@sheemc.cn.
⁶ Department of Medicine Cardiology Division, University of Maryland School of Medicine, 20 Penn St. HSFII S005, Baltimore, MD, 21201, USA.

PMID: 31954217
DOI: 10.1016/j.ecoenv.2019.110154

Associations between fine particulate matter constituents and daily cardiovascular mortality in Shanghai, China

Cuiping Wang et al. Ecotoxicol Environ Saf. 2020.

. 2020 Mar 15:191:110154.

doi: 10.1016/j.ecoenv.2019.110154. Epub 2020 Jan 15.

Authors

Cuiping Wang¹, Lipeng Hao², Cong Liu¹, Renjie Chen¹, Weidong Wang¹, Yichen Chen², Yining Yang³, Xia Meng⁴, Qingyan Fu⁵, Zhekang Ying⁶, Haidong Kan¹

Affiliations

¹ School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, 200032, China.
² Shanghai Pudong New Area Center for Disease Control and Prevention, Fudan University Pudong Institute of Preventive Medicine, Shanghai, 200136, China.
³ Beijing No.171 High School, Beijing, 100013, China.
⁴ School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, 200032, China. Electronic address: mengxxia@gmail.com.
⁵ Shanghai Environmental Monitoring Center, Shanghai, 200235, China. Electronic address: qingyanf@sheemc.cn.
⁶ Department of Medicine Cardiology Division, University of Maryland School of Medicine, 20 Penn St. HSFII S005, Baltimore, MD, 21201, USA.

PMID: 31954217
DOI: 10.1016/j.ecoenv.2019.110154

Abstract

Limited evidence is available for the associations between fine particulate matter (PM_2.5) constituents and daily cardiovascular disease (CVD) mortality in China. In present study, a time-series analysis was conducted to evaluate the associations of PM_2.5 constituents (two carbonaceous fractions, eight water-soluble inorganic ions and fifteen elements) with daily CVD mortality in Pudong New Area of Shanghai, China, from 2014 to 2016. Results showed that the effect estimates for the associations of PM_2.5 and its constituents with CVD mortality were generally strongest when using the exposures of the previous two day concentrations. The associations of organic carbon, sulfate, ammonia, potassium, copper, arsenic, and lead with daily CVD mortality were robust to the adjustment of PM_2.5 total mass, their collinearity with PM_2.5 total mass, and criteria gaseous air pollutants. An interquartile range increase in the previous two day concentrations of PM_2.5, organic carbon, sulfate, ammonia, potassium, copper, arsenic, and lead were associated with significant increments of 2.21% (95% confidence interval [95%CI]: 0.54%, 3.88%), 2.83% (95% CIs: 1.16%, 4.50%), 1.90% (95% CIs: 0.35%, 3.45%), 2.29% (95% CIs: 0.80%, 3.77%), 0.94% (95% CIs: 0.13%, 1.75%), 1.53% (95% CIs: 0.37%, 2.69%), 2.08% (95% CIs: 0.49%, 3.68%) and 1.98% (95% CIs: 0.49%, 3.47%) in daily CVD mortality, respectively, in single-pollutant models. In conclusion, this study suggested that organic carbon, sulfate, ammonia, potassium, copper, arsenic, and lead might be mainly responsible for the associations between short-term PM_2.5 exposures and increased CVD mortality in Shanghai, China.

Keywords: Cardiovascular mortality; Constituents; Fine particulate matter; Time-series study.

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Conflict of interest statement

Declaration of competing interest The authors declared no conflicts of interests.

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Associations between fine particulate matter constituents and daily cardiovascular mortality in Shanghai, China

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Associations between fine particulate matter constituents and daily cardiovascular mortality in Shanghai, China

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Conflict of interest statement

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