Evidence for Gastrointestinal Infection of SARS-CoV-2

doi:10.1053/j.gastro.2020.02.055

Comment

. 2020 May;158(6):1831-1833.e3.

doi: 10.1053/j.gastro.2020.02.055. Epub 2020 Mar 3.

Evidence for Gastrointestinal Infection of SARS-CoV-2

Fei Xiao¹, Meiwen Tang², Xiaobin Zheng³, Ye Liu⁴, Xiaofeng Li⁵, Hong Shan⁶

Affiliations

¹ Department of Infectious Diseases, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Guangdong Provincial Key Laboratory of Biomedical Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
² Department of Hematology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
³ Department of Respiratory and Critical Care Medicine, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
⁴ Department of Pathology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China. Electronic address: ly77219@163.com.
⁵ Department of Gastroenterology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China. Electronic address: zdwylxf@163.com.
⁶ Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Guangdong Provincial Key Laboratory of Biomedical Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Department of Interventional Medicine, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China. Electronic address: shanhong@mail.sysu.edu.cn.

PMID: 32142773
PMCID: PMC7130181
DOI: 10.1053/j.gastro.2020.02.055

Comment

Evidence for Gastrointestinal Infection of SARS-CoV-2

Fei Xiao et al. Gastroenterology. 2020 May.

. 2020 May;158(6):1831-1833.e3.

doi: 10.1053/j.gastro.2020.02.055. Epub 2020 Mar 3.

Authors

Fei Xiao¹, Meiwen Tang², Xiaobin Zheng³, Ye Liu⁴, Xiaofeng Li⁵, Hong Shan⁶

Affiliations

¹ Department of Infectious Diseases, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Guangdong Provincial Key Laboratory of Biomedical Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
² Department of Hematology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
³ Department of Respiratory and Critical Care Medicine, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China.
⁴ Department of Pathology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China. Electronic address: ly77219@163.com.
⁵ Department of Gastroenterology, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China. Electronic address: zdwylxf@163.com.
⁶ Guangdong Provincial Engineering Research Center of Molecular Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Guangdong Provincial Key Laboratory of Biomedical Imaging, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China; Department of Interventional Medicine, the Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong Province, China. Electronic address: shanhong@mail.sysu.edu.cn.

PMID: 32142773
PMCID: PMC7130181
DOI: 10.1053/j.gastro.2020.02.055

No abstract available

Keywords: ACE2; Gastrointestinal Infection; Oral-Fecal Transmission; SARS-CoV-2.

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Figures

**Figure 1**
Images of histologic and immunofluorescent staining of gastrointestinal tissues. Shown are images of histologic and immunofluorescent staining of esophagus, stomach, duodenum, and rectum. The scale bar in the histologic image represents 100 μm. The scale bar in the immunofluorescent image represents 20 μm.

See this image and copyright information in PMC

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References

1. Holshue M.L. N Engl J Med. 2020;382:929–936. - PMC - PubMed
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[1] Holshue M.L. N Engl J Med. 2020;382:929–936. - PMC - PubMed

[2] Holshue M.L. N Engl J Med. 2020;382:929–936. - PMC - PubMed

[3] Zhou P. Nature. 2020;579:270–273. - PMC - PubMed

[4] Zhou P. Nature. 2020;579:270–273. - PMC - PubMed

[5] Harmer D. FEBS Lett. 2002;532:107–110. - PubMed

[6] Harmer D. FEBS Lett. 2002;532:107–110. - PubMed

[7] Yan R. Science. 2020;367:1444–1448. - PMC - PubMed

[8] Yan R. Science. 2020;367:1444–1448. - PMC - PubMed

[9] Li Q. N Engl J Med. 2020;382:1199–1207. - PMC - PubMed

[10] Li Q. N Engl J Med. 2020;382:1199–1207. - PMC - PubMed

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Evidence for Gastrointestinal Infection of SARS-CoV-2

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Evidence for Gastrointestinal Infection of SARS-CoV-2

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