doi: 10.1016/j.autneu.2020.102658.
Epub 2020 Feb 26.
Serotonin and substance P: Synergy or competition in the control of breathing
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- PMID: 32145695
- DOI: 10.1016/j.autneu.2020.102658
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Serotonin and substance P: Synergy or competition in the control of breathing
Auton Neurosci.
2020 May.
Abstract
Numerous neurotransmitters identified in the central nervous system play role in ventilatory control. This mini-review focuses on the respiratory effects of two neurotransmitters: serotonin (5-HT) and substance P (SP). We discuss their co-localization in medullary raphe nuclei, expression of proper receptors within the specific regions of respiratory related structures and contribution to respiratory rhythmogenesis.
Keywords: Larynx; Pre-Bötzinger complex; Raphe nuclei; Serotonin; Substance P.
Copyright © 2020 Elsevier B.V. All rights reserved.
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