Pegaspargase
- PMID: 32697465
- Bookshelf ID: NBK559660
Pegaspargase
Excerpt
No information is available on the clinical use of pegaspargase during breastfeeding. Because pegaspargase is a large protein molecule with a molecular weight of about 140,000 Da, the amount in milk is likely to be very low.[1] It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal.[2] Polyethylene glycol is not excreted into breastmilk.[3] However, the manufacturer recommends that the drug not be used during breastfeeding and for 1 month after the last dose.
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