Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma?
- PMID: 32937686
- PMCID: PMC7641560
- DOI: 10.3350/cmh.2020.0143
Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma?
Keywords: Carcinoma, Hepatocellular; EMT; GSK3β; PI3K inhibitor.
Conflict of interest statement
Comment on
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Inhibition of PI3K/Akt signaling suppresses epithelial-to-mesenchymal transition in hepatocellular carcinoma through the Snail/GSK-3/beta-catenin pathway.Clin Mol Hepatol. 2020 Oct;26(4):529-539. doi: 10.3350/cmh.2019.0056n. Epub 2020 Aug 24. Clin Mol Hepatol. 2020. PMID: 32829570 Free PMC article.
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References
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- Ko E, Seo HW, Jung ES, Ju S, Kim BH, Cho H, et al. PI3Kδ is a therapeutic target in hepatocellular carcinoma. Hepatology. 2018;68:2285–2300. - PubMed
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