Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep;128(9):94003.
doi: 10.1289/EHP7160. Epub 2020 Sep 18.

Arsenic Exposure and Glucose Metabolism: Experimental Studies Suggest Implications for Type 2 Diabetes

Lindsey Konkel
Comment

Arsenic Exposure and Glucose Metabolism: Experimental Studies Suggest Implications for Type 2 Diabetes

Lindsey Konkel. Environ Health Perspect. 2020 Sep.
No abstract available

PubMed Disclaimer

Figures

False color transmission electron micrograph of a beta cell
Graphical abstract
False color transmission electron micrograph of a beta cell
This micrograph of a pancreatic β cell shows insulin granules in blue, mitochondria in green, and the nucleus in purple. Disruption of β cell function is one of several potential mechanisms that could explain the association between arsenic exposure and type 2 diabetes. Image: © Jose Luis Calvo/Science Source.
See this image and copyright information in PMC

Comment on

Similar articles

See all similar articles

Cited by

  • Update of the risk assessment of inorganic arsenic in food.
    EFSA Panel on Contaminants in the Food Chain (CONTAM); Schrenk D, Bignami M, Bodin L, Chipman JK, Del Mazo J, Grasl-Kraupp B, Hogstrand C, Hoogenboom LR, Leblanc JC, Nebbia CS, Nielsen E, Ntzani E, Petersen A, Sand S, Vleminckx C, Wallace H, Barregård L, Benford D, Broberg K, Dogliotti E, Fletcher T, Rylander L, Abrahantes JC, Gómez Ruiz JÁ, Steinkellner H, Tauriainen T, Schwerdtle T. EFSA Panel on Contaminants in the Food Chain (CONTAM), et al. EFSA J. 2024 Jan 18;22(1):e8488. doi: 10.2903/j.efsa.2024.8488. eCollection 2024 Jan. EFSA J. 2024. PMID: 38239496 Free PMC article.

References

    1. Navas-Acien A, Silbergeld EK, Streeter RA, Clark JM, Burke TA, Guallar E. 2006. Arsenic exposure and type 2 diabetes: a systematic review of the experimental and epidemiological evidence. Environ Health Perspect 114(5):641–648, PMID: 16675414, 10.1289/ehp.8551. - DOI - PMC - PubMed
    1. Castriota F, Acevedo J, Ferreccio C, Smith AH, Liaw J, Smith MT, et al. . 2018. Obesity and increased susceptibility to arsenic-related type 2 diabetes in Northern Chile. Environ Res 167:248–254, PMID: 30059859, 10.1016/j.envres.2018.07.022. - DOI - PMC - PubMed
    1. Grau-Perez M, Kuo C-C, Gribble MO, Balakrishnan P, Jones Spratlen M, Vaidya D, et al. . 2017. Association of low-moderate arsenic exposure and arsenic metabolism with incident diabetes and insulin resistance in the Strong Heart Family Study. Environ Health Perspect 125(12):127004, PMID: 29373862, 10.1289/EHP2566. - DOI - PMC - PubMed
    1. Castriota F, Rieswijk L, Dahlberg S, La Merrill MA, Steinmaus C, Smith MT, et al. . 2020. A state-of-the-science review of arsenic’s effects on glucose homeostasis in experimental models. Environ Health Perspect 128(1):16001, PMID: 31898917, 10.1289/EHP4517. - DOI - PMC - PubMed
    1. Maull EA, Ahsan H, Edwards J, Longnecker MP, Navas-Acien A, Pi J, et al. . 2012. Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review. Environ Health Perspect 120(12):1658–1670, PMID: 22889723, 10.1289/ehp.1104579. - DOI - PMC - PubMed
-